Plasma ammonia concentrations in extremely low birthweight infants in the first week after birth: secondary analysis from the ProVIDe randomized clinical trial
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Research"
DOI: 10.1038/s41390-019-0730-z
Abstract: Background Little is known about normative ammonia concentrations in extremely low birthweight (ELBW) babies and whether these vary with birth characteristics. We aimed to determine ammonia concentrations in ELBW babies in the first week after… read more here.
Keywords: extremely low; ammonia concentrations; birth; ammonia ... See more keywords
Pharmacokinetics/pharmacodynamics of L-ornithine phenylacetate in overt hepatic encephalopathy and the effect of plasma ammonia concentration reduction on clinical outcomes.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and translational science"
DOI: 10.1111/cts.13257
Abstract: Hepatic encephalopathy (HE) is a serious neurocognitive complication of liver dysfunction, often associated with elevated plasma ammonia. Ornithine phenylacetate (OP), a potent ammonia scavenger, is being evaluated for the treatment of acute/overt HE. The pharmacokinetics… read more here.
Keywords: ornithine phenylacetate; ammonia; plasma ammonia; hepatic encephalopathy ... See more keywords