Measurement of Free and Glucuronidated Cardamonin in Rat Plasma and Bile Using UPLC-MS/MS and Its Application to a Pharmacokinetic and Bile Excretion Study
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-019-9275-2
Abstract: A rapid and accurate ultra-high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry(UPLC-MS/MS) method was established and validated for the measurement of two forms of cardamonin, i.e., free and glucuronidated, in the plasma and bile of rats. Cardamonin… read more here.
Keywords: bile; measurement free; free glucuronidated; glucuronidated cardamonin ... See more keywords
Genetic and clinical features of patients with intrahepatic cholestasis caused by citrin deficiency
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2022-0616
Abstract: Abstract Objectives Citrin deficiency (CD) is an autosomal recessive disease caused by mutations of the SLC25A13 gene, plasma bile acid profiles detected by liquid chromatography-tandem mass spectrometry (LC-MS/MS) could be an efficient approach for early… read more here.
Keywords: cholestasis; plasma bile; citrin deficiency; intrahepatic cholestasis ... See more keywords