Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.8214
Abstract: Key Points Question Can plasma biomarker analytes be used in a low-resource community to improve clinical accuracy in diagnosing Alzheimer disease (AD)? Findings In this decision analytical modeling study of 746 Caribbean Hispanic individuals from… read more here.
Keywords: plasma biomarkers; alzheimer disease; plasma; evidence ... See more keywords
Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.3392
Abstract: This secondary analysis of a randomized clinical trial investigates the association of donanemab treatment with plasma biomarkers associated with Alzheimer disease. read more here.
Keywords: donanemab treatment; alzheimer disease; association donanemab; plasma biomarkers ... See more keywords
Novel plasma biomarkers associated with liver disease severity in adults with nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28776
Abstract: Despite the high prevalence of nonalcoholic fatty liver disease (NAFLD), therapeutic options and noninvasive markers of disease activity and severity remain limited. We investigated the association between plasma biomarkers and liver histology in order to… read more here.
Keywords: plasma biomarkers; severity; liver disease; hepatology ... See more keywords
Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change
Sign Up to like & getrecommendations! Published in 2022 at "Acta Neuropathologica"
DOI: 10.1007/s00401-022-02408-5
Abstract: Plasma biomarkers related to amyloid, tau, and neurodegeneration (ATN) show great promise for identifying these pathological features of Alzheimer’s Disease (AD) as shown by recent clinical studies and selected autopsy studies. We have evaluated ATN… read more here.
Keywords: change; plasma biomarkers; plasma; pathology ... See more keywords
Investigation of the Number of Tests Required for Assaying Plasma Biomarkers Associated with Alzheimer’s Disease Using Immunomagnetic Reduction
Sign Up to like & getrecommendations! Published in 2021 at "Neurology and Therapy"
DOI: 10.1007/s40120-021-00280-1
Abstract: Concentrations of plasma biomarkers associated with Alzheimer’s disease have been reported to be as low as several tens of picograms/milliliter (pg/ml). However, in assays measuring these biomarkers, it is likely that repeated measurements are necessary… read more here.
Keywords: associated alzheimer; plasma biomarkers; alzheimer disease; number ... See more keywords
Assessment of plasma biomarkers for their association with Multiple Sclerosis progression
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2017.01.008
Abstract: In a cross-sectional study involving 160 Multiple Sclerosis (MS) patients and 70 healthy controls we set out to determine the association of five blood biomarkers with MS risk and progression scores. High levels of Semaphorin3A… read more here.
Keywords: sclerosis; plasma biomarkers; assessment plasma; biomarkers association ... See more keywords
Plasma biomarkers associated with deployment trauma and its consequences in post-9/11 era veterans: initial findings from the TRACTS longitudinal cohort
Sign Up to like & getrecommendations! Published in 2022 at "Translational Psychiatry"
DOI: 10.1038/s41398-022-01853-w
Abstract: Mild traumatic brain injury (mTBI) is among the most common injuries sustained by post-9/11 veterans; however, these injuries often occur within the context of psychological trauma. Blast exposure, even in the absence of a diagnosable… read more here.
Keywords: biomarkers associated; deployment trauma; plasma biomarkers; gfap ... See more keywords
Novel plasma biomarkers improve discrimination of metabolic health independent of weight
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78478-w
Abstract: We sought to determine if novel plasma biomarkers improve traditionally defined metabolic health (MH) in predicting risk of cardiovascular disease (CVD) events irrespective of weight. Poor MH was defined in CATHGEN biorepository participants (n > 9300), a… read more here.
Keywords: plasma biomarkers; plasma; metabolic health; novel plasma ... See more keywords
Predicting amyloid PET and tau PET stages with plasma biomarkers
Sign Up to like & getrecommendations! Published in 2023 at "Brain"
DOI: 10.1093/brain/awad042
Abstract: Abstract Staging the severity of Alzheimer’s disease pathology using biomarkers is useful for therapeutic trials and clinical prognosis. Disease staging with amyloid and tau PET has face validity; however, this would be more practical with… read more here.
Keywords: plasma biomarkers; tau pet; pet stages; pet ... See more keywords
Novel plasma biomarkers in arrhythmogenic cardiomyopathy: the role of ST2 and GDF-15 in predicting biventricular involvement
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.0728
Abstract: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease characterized by fibrofatty replacement of the myocardium and ventricular arrhythmias. Biventricular (BiV) involvement in ARVC may lead to heart failure. This study aimed to… read more here.
Keywords: arvc; plasma biomarkers; sst2 gdf; novel plasma ... See more keywords
Plasma biomarkers for neurodegenerative disorders: ready for prime time?
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Psychiatry"
DOI: 10.1097/yco.0000000000000851
Abstract: Purpose of review Several plasma biomarkers for Alzheimer's disease and related disorders (ADRD) have demonstrated clinical and technical robustness. However, are they ready for clinical implementation? This review critically appraises current evidence for and against… read more here.
Keywords: plasma biomarkers; time; biomarkers neurodegenerative; plasma ... See more keywords