The clinical and pathological features of plasma cell myeloma post solid organ transplantation
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Hematology"
DOI: 10.1002/ajh.25988
Abstract: Plasma cell neoplasms (PCNs), comprising plasma cell myelomas (PCMs) and plasmacytomas, which occur after solid organ transplantation, represent rare subtypes of monomorphic post‐transplant lymphoproliferative disorders (M‐PTLDs). Data regarding the clinical and pathological features of post‐transplant… read more here.
Keywords: solid organ; organ transplantation; plasma cell; post ... See more keywords
Investigation of Plasma cell‐free cancer genome chromosomal instability as a tool for targeted minimally invasive biomarkers for primary liver cancer diagnoses
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3142
Abstract: To characterize plasma cell‐free cancer genome chromosomal instabilities (CIN) in patients with liver cancer and to evaluate the potential of CIN as minimally invasive biomarkers for primary liver cancer (PLC) diagnoses. read more here.
Keywords: cancer genome; plasma cell; cell free; free cancer ... See more keywords
miR‐148a weaves its thread into the plasma cell fate
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202149240
Abstract: The plasma cells (PC) are characterized by their rarity, their formidable capacity to continuously secrete massive amounts of antibodies and the potential to live through the whole life span of the organism that houses them.… read more here.
Keywords: weaves thread; plasma; mir 148a; 148a weaves ... See more keywords
Citrulline enteral administration markedly reduces immunosuppressive extrafollicular plasma cell differentiation in a preclinical model of sepsis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250154
Abstract: The sustained immunosuppression associated with severe sepsis favors an increased susceptibility to secondary infections and remains incompletely understood. Plasmablast and plasma cell subsets, whose primary function is to secrete antibodies, have emerged as important suppressive… read more here.
Keywords: sepsis; cell; administration; plasma cell ... See more keywords
Noninvasive detection of brain gliomas using plasma cell‐free DNA 5‐hydroxymethylcytosine sequencing
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DOI: 10.1002/ijc.34401
Abstract: Liquid biopsy techniques based on deep sequencing of plasma cell‐free DNA (cfDNA) could detect the low‐frequency somatic mutations and provide an accurate diagnosis for many cancers. However, for brain gliomas, reliable performance of these techniques… read more here.
Keywords: brain gliomas; cell free; plasma cell; gliomas ... See more keywords
Sequential development of monoclonal B cell lymphocytosis-derived small lymphocytic lymphoma and plasma cell leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Hematology"
DOI: 10.1007/s00277-018-3248-2
Abstract: Dear Editor, Accumulating evidence suggests that monoclonal B cell lymphocytosis (MBL) is a precursor condition for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/ SLL). Other MBL-derived B cell malignancies are quite rare, and the clonal evolution… read more here.
Keywords: cell; mbl; plasma cell; cll sll ... See more keywords
Therapeutic strategies for durable response in plasma cell granulomas in the central nervous system
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Hematology"
DOI: 10.1007/s00277-018-3490-7
Abstract: Dear Editor, Plasma cell granuloma or inflammatory myofibroblastic tumor (IMT) is a rare histopathologic diagnosis characterized by heavy lymphoplasmacytic inflammatory infiltration with myofibroblastic spindle cells [1–3]. Here, we present a challenging case of IMT with… read more here.
Keywords: imt; central nervous; response; plasma cell ... See more keywords
Plasma cell myeloma with pure lymphocyte-like morphology
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04322-w
Abstract: Dear Editor, Plasma cell myeloma can have various morphological patterns, with six histological subtypes: well-differentiated (Marschalko), small cell, cleaved, polymorphous, asynchronous, and blastic [1]. Small-cell-type plasma cell myeloma (SC-PCM) predominantly consists of small plasma cells… read more here.
Keywords: plasma; cell myeloma; plasma cell; pure lymphocyte ... See more keywords
Development of Monoclonal Antibodies: The Dawn of mAb Rule
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DOI: 10.1007/s10620-017-4478-1
Abstract: Underlying most major therapeutic advances are fundamental discoveries that shake scientific discourse to its core, usually generating Nobel prizes and entirely new fields of study. In this eighth installment of the series entitled ‘‘Paradigm Shifts… read more here.
Keywords: monoclonal antibodies; antibody production; antibody; plasma cell ... See more keywords
Assessing genome-wide copy number aberrations and copy-neutral loss-of-heterozygosity as best practice: An evidence-based review from the Cancer Genomics Consortium working group for plasma cell disorders.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2018.07.002
Abstract: BACKGROUND Plasma cell neoplasms (PCNs) encompass a spectrum of disorders including monoclonal gammopathy of undetermined significance, smoldering myeloma, plasma cell myeloma, and plasma cell leukemia. Molecular subtypes have been defined by recurrent cytogenetic abnormalities and… read more here.
Keywords: working group; plasma cell; practice; cma ... See more keywords
Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs.
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DOI: 10.1016/j.celrep.2020.107876
Abstract: Summary The transition from the follicular B to the plasma cell stage is associated with large-scale changes in cell morphology. Here, we examine whether plasma cell development is also associated with changes in nuclear architecture. We… read more here.
Keywords: chromosomal hubs; plasma cell; inter chromosomal; cell ... See more keywords