Early-Life Iron Status Modulates Metabolomics Profiles of Plasma and Cerebrospinal Fluid in a Piglet Model
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DOI: 10.1093/cdn/nzaa050_018
Abstract: The study aims to determine the impact of iron status on plasma and cerebrospinal fluid (CSF) metabolites in a piglet model. On postnatal day (PD) 1, 30 crossbred piglets (15 male/female) were blocked by sex… read more here.
Keywords: piglet model; iron status; iron; plasma cerebrospinal ... See more keywords
Plasma and cerebrospinal fluid pharmacokinetics of ondansetron in humans
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DOI: 10.1111/bcp.14412
Abstract: Changes in serotonergic sensory modulation associated with overexpression of 5‐HT3 receptors in the central nervous system (CNS) have been implicated in the pathophysiology of neuropathic pain after peripheral nerve damage. 5‐HT3 receptor antagonists such as… read more here.
Keywords: pharmacokinetics ondansetron; cns; fluid pharmacokinetics; plasma cerebrospinal ... See more keywords
Plasma and cerebrospinal fluid tau and neurofilament concentrations in rapidly progressive neurological syndromes: a neuropathology‐based cohort
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DOI: 10.1111/ene.13389
Abstract: Cerebrospinal fluid (CSF) tau and neurofilament light chain (NF‐L) proteins have proved to be reliable biomarkers for neuronal damage; however, there is a strong need for blood‐based tests. read more here.
Keywords: fluid tau; tau neurofilament; neurofilament concentrations; plasma cerebrospinal ... See more keywords
Assessment of Plasma and Cerebrospinal Fluid Biomarkers in Different Stages of Alzheimer’s Disease and Frontotemporal Dementia
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DOI: 10.3390/ijms24021226
Abstract: Alzheimer’s disease (AD) is the primary type of dementia, followed by frontotemporal lobar degeneration (FTLD). They share some clinical characteristics, mainly at the early stages. So, the identification of early, specific, and minimally invasive biomarkers… read more here.
Keywords: plasma cerebrospinal; cerebrospinal fluid; alzheimer disease; dementia ... See more keywords
Plasma and Cerebrospinal Fluid Concentrations of Micafungin Administered at High Doses in Critically Ill Infants with Systemic Candidiasis: A Pooled Analysis of Two Studies
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DOI: 10.3390/ph16030472
Abstract: Background: Neonates may require higher doses of micafungin than adults to reach the therapeutic effect for increased plasma clearance. Only poor and inconclusive data are available still now to support this hypothesis, especially with regard… read more here.
Keywords: candidiasis; cerebrospinal fluid; systemic candidiasis; plasma cerebrospinal ... See more keywords