Analysis of 52 240 source plasma donors of convalescent COVID‐19 plasma: Sex, ethnicity, and age association with initial antibody levels and rate of dissipation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21998
Abstract: COVID‐19 convalescent plasma (CCP) was approved under emergency authorization to treat critically ill patients with COVID‐19 in the United States in 2020. We explored the demographics of donors contributing plasma for a hyperimmune, plasma‐derived therapy… read more here.
Keywords: 240 source; analysis 240; plasma; plasma donors ... See more keywords
SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donors
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Internal Medicine"
DOI: 10.1016/j.ejim.2021.05.010
Abstract: Elucidating the characteristics of human immune response against SARS-CoV-2 is of high priority and relevant for determining vaccine strategies. We report the results of a follow-up evaluation of anti-SARS-CoV-2 antibodies in 148 convalescent plasma donors… read more here.
Keywords: persistence; antibody; spike; sars cov ... See more keywords
Antibody response against SARS-CoV-2 in convalescent plasma donors: Can we predict subjects’ eligibility?
Sign Up to like & getrecommendations! Published in 2021 at "Hematology, Transfusion and Cell Therapy"
DOI: 10.1016/j.htct.2021.07.008
Abstract: Introduction : As the Coronavirus Disease 2019 (COVID-19) pandemic unfolds around the world; answers related to the antibody response against the virus are necessary to develop treatment and prophylactic strategies. We attempted to understand part… read more here.
Keywords: convalescent plasma; plasma donors; antibody response; response ... See more keywords
Convalescent plasma donors show enhanced cross‐reactive neutralizing antibody response to antigenic variants of SARS‐CoV‐2 following immunization
Sign Up to like & getrecommendations! Published in 2022 at "Transfusion"
DOI: 10.1111/trf.16934
Abstract: The therapeutic benefit of convalescent plasma (CP) therapy to treat COVID‐19 may derive from neutralizing antibodies (nAbs) to SARS‐CoV‐2. To investigate the effects of antigenic variation on neutralization potency of CP, we compared nAb titers… read more here.
Keywords: immunization; plasma donors; convalescent plasma; sars cov ... See more keywords
How to convert whole‐blood donors to plasma donors: An investigation of the mechanisms of awareness of need for plasma and donors' perception of response efficacy
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DOI: 10.1111/trf.17316
Abstract: Blood donation services need to increase plasma donations to match the rising demand. However, evidence on how to best recruit donors among whole‐blood donors is limited. Therefore, this study evaluated the effectiveness of a conversion… read more here.
Keywords: blood donors; need plasma; plasma donors; whole blood ... See more keywords
Understanding donation frequency: insights from current plasma donors
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DOI: 10.1111/vox.12861
Abstract: Encouraging existing plasma donors to donate more frequently is a key objective for blood donation services committed to expanding yield through voluntary non‐remunerated plasmapheresis donation. This requires an understanding of donors’ perspectives on their current… read more here.
Keywords: understanding donation; donation; frequency insights; donation frequency ... See more keywords