Fundamentals of Pharmacokinetics to Assess the Correlation Between Plasma Drug Concentrations and Different Blood Sampling Methods
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2550-y
Abstract: PurposeVarious blood collection methods were developed and used in the pharmacokinetic evaluation of drugs. However, the influence of different blood sampling methods on plasma drug concentrations has not been clarified. In the present study, we… read more here.
Keywords: sampling methods; drug; different blood; blood ... See more keywords
Indexed plasma drug concentrations for drug adherence screening in hypertensive patients.
Sign Up to like & getrecommendations! Published in 2018 at "Annales de cardiologie et d'angeiologie"
DOI: 10.1016/j.ancard.2018.04.020
Abstract: AIM Due to its high sensitivity, qualitative plasma drug screening by liquid chromatography/tandem mass spectrometry may not be able to distinguish same-day drug intake from drug use on preceding days and cause misclassifications of drug… read more here.
Keywords: drug adherence; drug; drug concentrations; hypertensive patients ... See more keywords
Plasma Drug Concentrations in Patients with Pulmonary Arterial Hypertension on Combination Treatment
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DOI: 10.1159/000470916
Abstract: Background: Combination therapy with the phosphodiesterase type 5 inhibitors (PDE-5i) sildenafil or tadalafil and the endothelin receptor antagonists (ERA) bosentan, ambrisentan, or macitentan may cause mutual pharmacokinetic interactions in patients with pulmonary arterial hypertension (PAH).… read more here.
Keywords: combination; mom; drug concentrations; plasma drug ... See more keywords