Plasma exosomes stimulate breast cancer metastasis through surface interactions and activation of FAK signaling
Sign Up to like & getrecommendations! Published in 2018 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-018-5043-0
Abstract: PurposeThe interaction between malignant cells and surrounding healthy tissues is a critical factor in the metastatic progression of breast cancer (BC). Extracellular vesicles, especially exosomes, are known to be involved in inter-cellular communication during cancer… read more here.
Keywords: cancer; fak signaling; plasma exosomes; breast cancer ... See more keywords
Plasma exosomes regulate systemic blood pressure in rats.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.06.075
Abstract: Exosomes, the smallest extracellular vesicle, contain various molecules and mediate cell-cell communication. A number of studies demonstrate exosomes are involved in important physiological and pathological processes. Moreover, microRNA (miRNA) regulating hypertension development through the suppression… read more here.
Keywords: systemic blood; derived exosomes; blood pressure; plasma exosomes ... See more keywords
Small RNA expression patterns in seminal plasma exosomes isolated from semen containing spermatozoa with cytoplasmic droplets versus regular exosomes in boar semen.
Sign Up to like & getrecommendations! Published in 2021 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2021.09.031
Abstract: Multiple physiological pathways are controlled by exosomes. Exosomes may be found in seminal plasma where they carry functional molecules to the sperm, such as microRNAs (miRNAs). Sperm cytoplasmic droplets (CDs) are remnants of cytoplasm, and… read more here.
Keywords: ssc; seminal plasma; ssc mir; plasma exosomes ... See more keywords
Integrated Pipeline of Rapid Isolation and Analysis of Human Plasma Exosomes for Cancer Discrimination Based on Deep Learning of MALDI-TOF MS Fingerprints.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04762
Abstract: Plasma exosomes have shown great potential for liquid biopsy in clinical cancer diagnosis. Herein, we present an integrated strategy for isolating and analyzing exosomes from human plasma rapidly and then discriminating different cancers excellently based… read more here.
Keywords: cancer; deep learning; based deep; human plasma ... See more keywords
Artificial Intelligence-Based Major Depressive Disorder (MDD) Diagnosis Using Raman Spectroscopic Features of Plasma Exosomes.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00215
Abstract: In vitro diagnosis using biomarkers for major depressive disorder (MDD) can offer considerable advantages in overcoming the lack of objective tests for depression and treating more patients. Plasma exosomes can be novel biomarkers for MDD… read more here.
Keywords: mdd diagnosis; diagnosis; plasma exosomes; diagnosis using ... See more keywords
A novel brain targeted plasma exosomes enhance the neuroprotective efficacy of edaravone in ischemic stroke.
Sign Up to like & getrecommendations! Published in 2021 at "IET nanobiotechnology"
DOI: 10.1049/nbt2.12003
Abstract: Ischemic stroke is often involved in the excessive production of reactive oxygen species (ROS), which aggravate ischemic injury. Edaravone (EDV) as an efficient free radical scavenger has demonstrated the effective neuroprotective effects in the therapy… read more here.
Keywords: ischemic stroke; edv; edaravone; brain ... See more keywords
Plasma exosomes induce inflammatory immune response in patients with acute myocardial infarction.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2021.1912102
Abstract: Exosomes are a kind of nanoscale extracellular vesicles with diameters of 30-100 nm and act as intracellular communication vehicles to influence cellular activities. Emerging pieces of evidence have indicated that exosomes play important roles in inflammation.… read more here.
Keywords: myocardial infarction; immune response; acute myocardial; inflammatory immune ... See more keywords
Expression of PD-L1 in plasma exosomes of NSCLC patients and its associations with PD-L1 expression of corresponding tumour tissues
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz239.049
Abstract: Abstract Background The aim of this study was to research whether there was expression of PD-L1 in plasma exosome of NSCLC patients and whether its expression can partly represent PD-L1 expression of corresponding lung tumor… read more here.
Keywords: nsclc patients; tumor tissues; exosomal expression; expression ... See more keywords
Plasma Exosomes From HLA-Sensitized Kidney Transplant Recipients Contain mRNA Transcripts Which Predict Development of Antibody-Mediated Rejection
Sign Up to like & getrecommendations! Published in 2017 at "Transplantation"
DOI: 10.1097/tp.0000000000001834
Abstract: Background Sensitization to HLA remains a significant immunologic barrier to successful transplantation. Identifying immune mechanisms responsible for antibody-mediated rejection (AMR) is an important goal. Here, we explored the possibility of predicting the risk for AMR… read more here.
Keywords: mediated rejection; kidney transplant; rejection; antibody mediated ... See more keywords
Identification of plasma exosomes long non-coding RNA HAGLR and circulating tumor cells as potential prognosis biomarkers in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Translational cancer research"
DOI: 10.21037/32462
Abstract: Background: The main purpose of this study was to identify the correlation between the expression of long non-coding RNA (lncRNA) HAGLR in plasma exosomes and the detection rate of circulating tumor cells (CTCs) in patients… read more here.
Keywords: cell; long non; non coding; cancer ... See more keywords
Plasma Exosomes from Children with Atopic Dermatitis May Promote Apoptosis of Keratinocytes and Secretion of Inflammatory Factors in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Clinical, Cosmetic and Investigational Dermatology"
DOI: 10.2147/ccid.s380205
Abstract: Purpose Exosomes are important regulators of keratinocytes (KCs) that have been implicated in a variety of skin disorders. The effect of circulatory exosomes on KCs in pediatric atopic dermatitis (AD) has not been well studied.… read more here.
Keywords: apoptosis; plasma exosomes; healthy controls; atopic dermatitis ... See more keywords