Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels
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DOI: 10.3389/fimmu.2022.1070476
Abstract: Introduction Hemophilia A (HA) is the most common X-linked bleeding disorder, occurring in 1 in 5,000 live male births and affecting >1 million individuals worldwide. Although advances in protein-based HA therapeutics have improved health outcomes,… read more here.
Keywords: plasma fviii; fviii; bone marrow; fviii levels ... See more keywords