Elevated plasma GDF15 combined with FGF21 suggests mitochondrial dysfunction in a subgroup of anorexia nervosa patients
Sign Up to like & getrecommendations! Published in 2025 at "Translational Psychiatry"
DOI: 10.1038/s41398-025-03425-0
Abstract: Growth and differentiation factor 15 (GDF15) is a significant player in cellular stress and energy homeostasis. GDF15 is elevated in cancer cachexia, chemotherapy-induced anorexia, hyperemesis gravidarum, and mitochondrial disorders. Here we analyze GDF15 in anorexia… read more here.
Keywords: gdf15; plasma gdf15; high gdf15; mitochondrial dysfunction ... See more keywords
Growth differentiation factor 15 is not modified after weight loss induced by liraglutide in South Asians and Europids with type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2024 at "Experimental Physiology"
DOI: 10.1113/ep091815
Abstract: Glucagon‐like peptide‐1 receptor (GLP‐1R) agonists induce weight loss in patients with type 2 diabetes mellitus (T2DM), but the underlying mechanism is unclear. Recently, the mechanism by which metformin induces weight loss could be explained by… read more here.
Keywords: weight loss; plasma gdf15; gdf15 levels; south asians ... See more keywords
Correlation of plasma GDF15 with aging, organ disfunction, sarcopenia, and postoperative infectious complication in patients with esophageal cancer.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.e16088
Abstract: e16088 Background: The age of cancer incidence is increasing every year. Along with it, cancer patients getting has more comorbidity and decreasing muscle strength which may lead to increase postoperative complications. Especially, since esophageal cancer… read more here.
Keywords: cancer; gdf15; plasma gdf15; infectious complication ... See more keywords
Heightened levels of plasma growth differentiation factor 15 in men living with HIV
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DOI: 10.14814/phy2.15293
Abstract: Plasma biomarkers that reflect energy balance disorders in people living with HIV (PLWH) remain limited. Growth differentiation factor 15 (GDF15) abundance in plasma of mice and humans induces negative energy balance but also becomes highly… read more here.
Keywords: plasma gdf15; hiv; gdf15; levels plasma ... See more keywords
Effect of metabolic disturbances on the plasma concentration and hepatic expression of the appetite-reducing hormone growth differentiation factor-15 (GDF15) in dairy cows.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of dairy science"
DOI: 10.3168/jds.2025-27481
Abstract: Early-lactating dairy cows are vulnerable to metabolic dysfunctions and diseases and the consequent negative effects of these disturbances on appetite. The exaggerated response of early-lactating cows to metabolic disturbances is illustrated by their response to… read more here.
Keywords: metabolic disturbances; effect; gdf15; plasma gdf15 ... See more keywords