Secondary IgA Nephropathy Shares the Same Immune Features With Primary IgA Nephropathy
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DOI: 10.1016/j.ekir.2019.10.012
Abstract: Introduction Galactose-deficient IgA1 (Gd-IgA1) and related IgA/IgG immune complexes have been identified as the key drivers in the pathogenesis of IgA nephropathy (IgAN). However, their roles in the development of secondary IgAN are still unknown.… read more here.
Keywords: plasma iga1; iga nephropathy; igg; iga1 ... See more keywords
Diagnostic Potential of Plasma IgA1 O-Glycans in Discriminating IgA Nephropathy From Other Glomerular Diseases and Healthy Participants
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.871615
Abstract: Background: Aberrant O-glycosylation of IgA1 plays an important role in IgA nephropathy pathogenesis. Previous proteomic studies analyzed O-glycans of the circulating IgA1 hinge region and found that the N-acetylgalactosamine (GalNAc) and galactose numbers in the… read more here.
Keywords: healthy participants; iga nephropathy; iga; plasma iga1 ... See more keywords