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Effect of mixed-mode and surface-modified column chromatography on virus filtration performance

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Published in 2021 at "Biochemical Engineering Journal"

DOI: 10.1016/j.bej.2021.108034

Abstract: Abstract Virus filtration is a critical process in the production of biotherapeutics and drug products derived by plasma fractionation. The processing steps upstream of virus removal filtration impact the filterability (throughput and flux) of process… read more here.

Keywords: mixed mode; filterability; chromatography; filtration ... See more keywords