Regulation of signal transduction by gangliosides in lipid rafts: focus on GM3–IR and GM1–TrkA interactions
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14532
Abstract: The interactions between gangliosides and proteins belonging to the same or different lipid domains and their influence on physiological and pathological states have been analysed in detail. A well‐known factor impacting on lipid–protein interactions and… read more here.
Keywords: gm1 trka; signal transduction; gm1; regulation signal ... See more keywords
Terahertz Spectroscopy Sheds Light on Real-Time Exchange Kinetics Occurring through Plasma Membrane during Photodynamic Therapy Treatment.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300589
Abstract: Methods to follow in real time complex processes occurring along living cell membranes such as cell permeabilization are rare. Here, the terahertz spectroscopy reveals early events in plasma membrane alteration generated during photodynamic therapy (PDT)… read more here.
Keywords: spectroscopy; terahertz spectroscopy; real time; plasma membrane ... See more keywords
Simultaneous co-overexpression of Saccharomyces cerevisiae septins Cdc3 and Cdc10 drives pervasive, phospholipid-, and tag-dependent plasma membrane localization.
Sign Up to like & getrecommendations! Published in 2023 at "Cytoskeleton"
DOI: 10.1002/cm.21762
Abstract: Septin proteins contribute to many eukaryotic processes involving cellular membranes. In the budding yeast Saccharomyces cerevisiae, septin hetero-oligomers interact with the plasma membrane (PM) almost exclusively at the future site of cytokinesis. While multiple mechanisms… read more here.
Keywords: localization; septins cdc3; septin; cdc3 cdc10 ... See more keywords
LEGO‐Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4‐Dihydroxyphenyl Moiety as Plasma Membrane H+‐ATPase Inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201700635
Abstract: The fungal plasma membrane H+‐ATPase (Pma1p) is a potential target for the discovery of new antifungal agents. Surprisingly, no structure–activity relationship studies for small molecules targeting Pma1p have been reported. Herein, we disclose a LEGO‐inspired… read more here.
Keywords: benzo; dihydroxyphenyl; plasma membrane; membrane atpase ... See more keywords
Rat Organic Anion Transport Protein 1A1 Interacts Directly With Organic Anion Transport Protein 1A4 Facilitating Its Maturation and Trafficking to the Hepatocyte Plasma Membrane
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30772
Abstract: Organic anion transport proteins (OATPs) on the basolateral surface of hepatocytes mediate uptake of a number of drugs and endogenous compounds. Previous studies showed that rat OATP1A1 (rOATP1A1) has a postsynaptic density protein, drosophila disc… read more here.
Keywords: anion transport; plasma membrane; roatp1a1; organic anion ... See more keywords
Structure and function of yeast and fungal Na+/H+ antiporters
Sign Up to like & getrecommendations! Published in 2018 at "IUBMB Life"
DOI: 10.1002/iub.1701
Abstract: Sodium proton antiporters (or sodium proton exchangers [NHEs]) are a critical family of membrane proteins that exchange sodium for protons across cell membranes. In yeast and plants, their primary function is to keep the sodium… read more here.
Keywords: fungal antiporters; function yeast; plasma membrane; function ... See more keywords
Label‐free surface‐enhanced Raman spectroscopy of lipid‐rafts from hepatocyte plasma membranes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Raman Spectroscopy"
DOI: 10.1002/jrs.5101
Abstract: Lipid rafts are sphingomyelin/cholesterol-rich domains present in the plasma membrane of eukaryotic cells. In the hepatocyte, it has been shown that these domains intervene and modify a wide range of functions from which cell signaling… read more here.
Keywords: surface enhanced; spectroscopy; raman spectroscopy; lipid rafts ... See more keywords
Native Planar Asymmetric Suspended Membrane for Single-Molecule Investigations: Plasma Membrane on a Chip.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205567
Abstract: Cellular plasma membranes, in their role as gatekeepers to the external environment, host numerous protein assemblies and lipid domains that manage the movement of molecules into and out of cells, regulate electric potential, and direct… read more here.
Keywords: single molecule; planar asymmetric; protein; membrane ... See more keywords
Enzyme-Activatable Polypeptide for Plasma Membrane Disruption and Antitumor Immunity Elicitation.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206912
Abstract: Enzyme-instructed self-assembly of bioactive molecules into nanobundles inside cells is conceived to potentially disrupt plasma membrane and subcellular structure. Herein, an alkaline phosphatase (ALP)-activatable hybrid of ICG-CF4 KYp is facilely synthesized by conjugating photosensitizer indocyanine… read more here.
Keywords: icg cf4; plasma; cf4 kyp; plasma membrane ... See more keywords
Overexpressed maltose transporters in laboratory and lager yeasts: Localization and competition with endogenous transporters
Sign Up to like & getrecommendations! Published in 2018 at "Yeast"
DOI: 10.1002/yea.3322
Abstract: Plain and fluorescently tagged versions of Agt1, Mtt1 and Malx1 maltose transporters were overexpressed in two laboratory yeasts and one lager yeast. The plain and tagged versions of each transporter supported similar transport activities, indicating… read more here.
Keywords: overexpressed maltose; maltose transporters; competition endogenous; transporters overexpressed ... See more keywords
Step-by-Step Protocol for Superparamagnetic Nanoparticle-Based Plasma Membrane Isolation from Eukaryotic Cell.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/7651_2019_211
Abstract: Here, we elaborate our detailed protocol for synthesis, functionalization, and application of superparamagnetic nanoparticle (SPMNP) for plasma membrane and lysosome isolation. We used standard thermal decomposition-based synthesis of iron oxide (Fe3O4) core SPMNP 1.0. Using… read more here.
Keywords: spmnp; membrane; isolation; superparamagnetic nanoparticle ... See more keywords