Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00161
Abstract: The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fatty-acid regulation, and detoxify ammonia—is susceptible to injuries induced by drugs and toxic substances. Although plasma metabolite profiles are increasingly investigated for… read more here.
Keywords: metabolism; metabolite changes; liver; plasma metabolite ... See more keywords
Potential Plasma Metabolite Biomarkers of Diabetic Nephropathy: Untargeted Metabolomics Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12111889
Abstract: Diabetic nephropathy (DN) is one of the specific complications of diabetes mellitus and one of the leading kidney-related disorders, often requiring renal replacement therapy. Currently, the tests commonly used for the diagnosis of DN, albuminuria… read more here.
Keywords: untargeted metabolomics; metabolite biomarkers; plasma metabolite; diabetic nephropathy ... See more keywords
Plasma Metabolite Signature Classifies Male LRRK2 Parkinson’s Disease Patients
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DOI: 10.3390/metabo12020149
Abstract: Parkinson’s disease (PD) is a progressive neurodegenerative disease, causing loss of motor and nonmotor function. Diagnosis is based on clinical symptoms that do not develop until late in the disease progression, at which point the… read more here.
Keywords: male lrrk2; metabolite signature; disease; plasma metabolite ... See more keywords
Plasma Metabolite Profiles Following Consumption of Animal Protein and Soybean-Based Diet in Hypercholesterolemic Postmenopausal Women
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DOI: 10.3390/metabo12030209
Abstract: Subjective reporting of food intake can be unreliable. No objective method is available to distinguish between diets differing in protein type. To address this gap, a secondary analysis of a randomized controlled cross-over feeding trial… read more here.
Keywords: plasma metabolite; protein type; animal protein; derived metabolites ... See more keywords
Plasma Metabolite Signatures in Male Carriers of Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease
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DOI: 10.3390/metabo13020267
Abstract: Both genetic and non-genetic factors are important in the pathophysiology of non-alcoholic fatty liver disease (NAFLD). The aim of our study was to identify novel metabolites and pathways associated with NAFLD by including both genetic… read more here.
Keywords: alcoholic fatty; non alcoholic; fatty liver; genetic variants ... See more keywords