Plasma neurofilament light chain levels are associated with depressive and anxiety symptoms in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Neurological Sciences"
DOI: 10.1007/s10072-022-05914-2
Abstract: The present study aimed to explore the association of plasma neurofilament light chain (NfL) levels with depression and anxiety in Parkinson’s disease (PD). This prospective study enrolled 116 patients with PD and 38 healthy controls,… read more here.
Keywords: light chain; anxiety; plasma neurofilament; parkinson disease ... See more keywords
Plasma neurofilament light chain levels predict improvement in late phase after stroke
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DOI: 10.1111/ene.14854
Abstract: Although functional recovery is most pronounced in the first 6 months after stroke, improvement is possible also in the late phase. The value of plasma neurofilament light chain (NfL), a biomarker of axonal injury and… read more here.
Keywords: improvement; neurofilament light; plasma neurofilament; light chain ... See more keywords
Plasma neurofilament light chain as a biomarker for fatal familial insomnia
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15302
Abstract: Fatal familial insomnia is a rare hereditary prion disease associated with the D178N‐129M PRNP mutation. Early diagnosis is difficult, because the clinical syndrome may overlap with affective disorders. In addition, most known cerebrospinal fluid biomarkers… read more here.
Keywords: neurofilament light; fatal familial; plasma neurofilament; familial insomnia ... See more keywords
Association of plasma neurofilament light chain with disease activity in chronic inflammatory demyelinating polyradiculoneuropathy
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15496
Abstract: This study was undertaken to explore associations between plasma neurofilament light chain (pNfL) concentration (pg/ml) and disease activity in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and examine the usefulness of pNfL concentrations in determining… read more here.
Keywords: neurofilament light; disease; disease activity; plasma neurofilament ... See more keywords
Plasma neurofilament light significantly decreases following treatment in Lyme neuroborreliosis and is not associated with persistent symptoms
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Neurology"
DOI: 10.1111/ene.15707
Abstract: Currently there is an unmet need for a highly standardized blood biomarker test to monitor treatment response in Lyme neuroborreliosis (LNB). Differentiating between active or past infection is challenged by the relatively high frequency of… read more here.
Keywords: lyme neuroborreliosis; persistent symptoms; neurofilament light; plasma neurofilament ... See more keywords
Associations of plasma neurofilament light chain and progranulin with frailty in older adults.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Geriatrics Society"
DOI: 10.1111/jgs.17604
Abstract: BACKGROUND In previous studies, plasma neurofilament light chain (NfL) and progranulin (PGRN) levels are associated with cognitive and physical impairment in older individuals. However, evidence of their relationships with frailty is lacking. This study aims… read more here.
Keywords: older adults; light chain; frailty; associations plasma ... See more keywords
Plasma neurofilament light chain concentration is increased and correlates with the severity of neuropathy in hereditary transthyretin amyloidosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Peripheral Nervous System"
DOI: 10.1111/jns.12350
Abstract: Hereditary transthyretin amyloidosis (ATTRm) causes a disabling peripheral neuropathy as part of a multisystem disorder. The recent development of highly effective gene silencing therapies has highlighted the need for effective biomarkers of disease activity to… read more here.
Keywords: neurofilament light; plasma neurofilament; transthyretin amyloidosis; hereditary transthyretin ... See more keywords
Longitudinal decline of plasma neurofilament light levels after antiretroviral initiation in people living with HIV
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13594
Abstract: This retrospective follow‐up study aims to investigate the dynamic longitudinal change of plasma neurofilament light (NfL) levels after antiretroviral therapy (ART) initiation in a cohort of people living with human immunodeficiency virus (HIV) (PWH). read more here.
Keywords: levels antiretroviral; neurofilament light; people living; plasma neurofilament ... See more keywords
Association of Plasma Neurofilament Light Chain With Glycaemic Control and Insulin Resistance in Middle-Aged Adults
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DOI: 10.3389/fendo.2022.915449
Abstract: Aims This study aimed to determine the association of plasma neurofilament light (NfL), a marker of neurodegeneration, with diabetes status and glycaemic parameters in people with normal glycaemia (NG), pre-diabetes (PD) and type 2 diabetes… read more here.
Keywords: nfl; plasma nfl; plasma neurofilament; plasma ... See more keywords
Evaluation of Plasma Neurofilament Light Chain Levels as a Biomarker of Neuronal Injury in the Active and Chronic Phases of Autoimmune Neurologic Disorders
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DOI: 10.3389/fneur.2022.689975
Abstract: Objective To evaluate plasma neurofilament light (NfL) levels in autoimmune neurologic disorders (AINDs) and autoimmune encephalitis (AE). Background Each particular neural autoantibody syndrome has a different clinical phenotype, making one unifying clinical outcome measure difficult… read more here.
Keywords: nfl levels; injury; nfl; plasma neurofilament ... See more keywords
Plasma Neurofilament Light Is Not Associated with Ongoing Neuroaxonal Injury or Cognitive Decline in Perinatally HIV Infected Adolescents: A Brief Report
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DOI: 10.3390/v14040671
Abstract: Despite combination antiretroviral therapy (cART), adolescents with perinatally acquired human immunodeficiency virus (PHIV) exhibit cerebral injury and cognitive impairment. Plasma neurofilament light (pNfL) is a biomarker identified as a promising marker associated with neuroaxonal injury… read more here.
Keywords: neuroaxonal injury; phiv adolescents; plasma neurofilament; cart ... See more keywords