Plasma neurofilament light levels correlate with white matter damage prior to Alzheimer’s disease: results from ADNI
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DOI: 10.1007/s40520-022-02095-y
Abstract: The blood biomarker neurofilament light (NFL) is one of the most widely used for monitoring Alzheimer's disease (AD). According to recent research, a higher NFL plasma level has a substantial predictive value for cognitive deterioration… read more here.
Keywords: plasma; neurofilament light; plasma nfl; association ... See more keywords
Plasma Neurofilament Light Chain and Clinical Diagnosis in Frontotemporal Dementia Syndromes
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DOI: 10.3233/jad-220272
Abstract: Background: Frontotemporal dementia (FTD) syndromes, mimics, phenocopy (phFTD), and slowly progressive behavioral variant FTD (bvFTD) can be difficult to distinguish clinically. Biomarkers such as neurofilament light chain (NfL) may be helpful. Objective: To study plasma… read more here.
Keywords: ftd syndromes; neurofilament light; ftd; frontotemporal dementia ... See more keywords
Association of Plasma Neurofilament Light Chain With Glycaemic Control and Insulin Resistance in Middle-Aged Adults
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DOI: 10.3389/fendo.2022.915449
Abstract: Aims This study aimed to determine the association of plasma neurofilament light (NfL), a marker of neurodegeneration, with diabetes status and glycaemic parameters in people with normal glycaemia (NG), pre-diabetes (PD) and type 2 diabetes… read more here.
Keywords: nfl; plasma nfl; plasma neurofilament; plasma ... See more keywords
Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders
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DOI: 10.3389/fnagi.2022.909552
Abstract: Objectives We employed quantitative susceptibility mapping (QSM) to assess iron deposition in parkinsonian disorders and explored whether combining QSM values and neurofilament light (NfL) chain levels can improve the accuracy of distinguishing Parkinson’s disease (PD)… read more here.
Keywords: parkinsonian disorders; susceptibility mapping; susceptibility; nfl levels ... See more keywords