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Published in 2025 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70311
Abstract: Human herpesvirus 6B (HHV‐6B) encephalitis is a rare but severe complication of hematopoietic cell transplantation. This study investigated the pathogenesis of HHV‐6B encephalitis by comparing plasma proteomic profiles of four pediatric patients with HHV‐6B encephalitis…
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Keywords:
encephalitis;
plasma proteomic;
reactivation;
transplantation ... See more keywords
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Published in 2020 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2019.12.008
Abstract: frequencies of mutation and copy number alterations, mutation signatures, intratumor heterogeneity, pathway alterations, and histology as well as overall survival were performed. We found that deleterious mutation burden was significantly greater in invasive ADC. Intratumor…
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Keywords:
plasma proteomic;
ia07 plasma;
proteomic glycomic;
glycomic autoantibody ... See more keywords
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Published in 2025 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.5c00785
Abstract: Advances in minimally invasive surgical techniques and precision oncology paradigms have significantly optimized the management of colorectal cancer (CRC). The advent of endoscopic superminimally invasive surgery (ESMIS) has led to comprehensive evaluations of its proteomic…
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Keywords:
colorectal cancer;
minimally invasive;
plasma proteomic;
invasive surgical ... See more keywords
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Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-025-56695-z
Abstract: Genomics can provide insight into the etiology of type 2 diabetes and its comorbidities, but assigning functionality to non-coding variants remains challenging. Polygenic scores, which aggregate variant effects, can uncover mechanisms when paired with molecular…
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Keywords:
related comorbidities;
plasma proteomic;
identification plasma;
type ... See more keywords
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Published in 2018 at "Aging Cell"
DOI: 10.1111/acel.12799
Abstract: To characterize the proteomic signature of chronological age, 1,301 proteins were measured in plasma using the SOMAscan assay (SomaLogic, Boulder, CO, USA) in a population of 240 healthy men and women, 22–93 years old, who…
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Keywords:
age healthy;
plasma proteomic;
age;
signature age ... See more keywords
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Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-1854
Abstract: Most patients treated with immune checkpoint blockade (ICB) do not have durable treatment responses, stressing a critical need to identify early non-invasive biomarkers of response. Circulating biomarkers provide easy access for serial monitoring and can…
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Keywords:
plasma proteomic;
response;
tumor;
melanoma patients ... See more keywords
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Published in 2023 at "JCI Insight"
DOI: 10.1172/jci.insight.165867
Abstract: Regular exercise leads to widespread salutary effects, and there is increasing recognition that exercise-stimulated circulating proteins can impart health benefits. Despite this, limited data exist regarding the plasma proteomic changes that occur in response to…
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Keywords:
exercise training;
plasma proteomic;
proteomic changes;
response ... See more keywords
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Published in 2025 at "Neurosurgery"
DOI: 10.1227/neu.0000000000003821
Abstract: BACKGROUND AND OBJECTIVES The diagnosis of spinal cord dysfunction in degenerative cervical myelopathy (DCM) is currently based on correlating clinical signs and symptoms with neuroimaging findings. Plasma proteomics represents an opportunity to establish objective, blood-based…
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Keywords:
dcm;
biobank;
plasma proteomic;
degenerative cervical ... See more keywords
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Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0236148
Abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is an unexplained chronic, debilitating illness characterized by fatigue, sleep disturbances, cognitive dysfunction, orthostatic intolerance and gastrointestinal problems. Using ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), we analyzed the plasma…
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Keywords:
plasma proteomic;
cfs;
association cfs;
proteomic profiling ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043570
Abstract: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection leads to a wide range of clinical manifestations and determines the need for personalized and precision medicine. To better understand the biological determinants of this heterogeneity, we explored…
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Keywords:
variables related;
covid severity;
plasma proteomic;
severity ... See more keywords
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Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26062428
Abstract: Mild cognitive impairment (MCI) is a clinical condition characterized by a decline in cognitive ability and progression of cognitive impairment. It is often considered a transitional stage between normal aging and Alzheimer’s disease (AD). This…
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Keywords:
cognitive impairment;
plasma proteomic;
machine;
model ... See more keywords