The Analysis of Plasma Proteomics for Luminal A Breast Cancer
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.70470
Abstract: Breast cancer is the prevailing malignancy among women, exhibiting a discernible escalation in incidence within our nation; hormone receptor‐positive (HR+) human epidermal growth factor receptor 2‐negative (HER2−) breast cancer is the most common subtype. In… read more here.
Keywords: cancer; luminal breast; breast cancer; plasma proteomics ... See more keywords
Plasma Proteomics to Identify Drug Targets and Potential Drugs for Retinal Artery Occlusion: An Integrated Analysis in the UK Biobank.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.4c00044
Abstract: Retinal artery occlusion (RAO), which is positively correlated with acute ischemic stroke (IS) and results in severe visual impairment, lacks effective intervention drugs. This study aims to perform integrated analysis using UK Biobank plasma proteome… read more here.
Keywords: biobank plasma; analysis; retinal artery; plasma proteomics ... See more keywords
Considering Measurement Time and Depth in diaPASEF Plasma Proteomics
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.5c00637
Abstract: Mass spectrometry (MS)-based plasma proteomics is a powerful approach to unraveling the biology or pathophysiology in large clinical cohorts. Implementation of data-independent acquisition in combination with ion mobility approaches (diaPASEF) has enabled high-throughput analysis with… read more here.
Keywords: experimental library; measurement time; depth; plasma proteomics ... See more keywords
Establishing Quality Control Procedures for Large-Scale Plasma Proteomics Analyses.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.3c00050
Abstract: Proteomics research has been transformed due to high-throughput liquid chromatography (LC-MS/MS) tandem mass spectrometry instruments combined with highly sophisticated automated sample preparation and multiplexing workflows. However, scaling proteomics experiments to large sample cohorts (hundreds to… read more here.
Keywords: quality control; plasma proteomics; plasma; establishing quality ... See more keywords
Plasma proteomics of acute tubular injury
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DOI: 10.1038/s41467-024-51304-x
Abstract: The kidney tubules constitute two-thirds of the cells of the kidney and account for the majority of the organ’s metabolic energy expenditure. Acute tubular injury (ATI) is observed across various types of kidney diseases and… read more here.
Keywords: tubular injury; plasma proteomics; injury; acute tubular ... See more keywords
Current landscape of plasma proteomics from technical innovations to biological insights and biomarker discovery
Sign Up to like & getrecommendations! Published in 2025 at "Communications Chemistry"
DOI: 10.1038/s42004-025-01665-1
Abstract: Plasma is a rich source of biomolecules, including proteins, that reflect both health and disease. Due to their key roles in biological processes, proteins hold significant potential as biomarkers, fueling the rise of plasma proteome… read more here.
Keywords: plasma; biomarker discovery; biological insights; plasma proteomics ... See more keywords
Single-Cell and Plasma Proteomics Do Not Differentiate Patients With and Without SARS-CoV-2 Antigenemia in Convalescence in a Cohort of 100 Patients
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaf515
Abstract: Abstract Plasma samples obtained approximately 3 (n = 100) and 12 months (n = 78) after acute SARS-CoV-2 infection were tested for S1, spike, and N antigens. There were no significant differences in plasma proteins… read more here.
Keywords: sars cov; cell plasma; single cell; plasma proteomics ... See more keywords
Pre-diagnostic plasma proteomics profile uncovers new biomarkers and mechanistic insights for incident kidney cancer.
Sign Up to like & getrecommendations! Published in 2025 at "International journal of surgery"
DOI: 10.1097/js9.0000000000003474
Abstract: BACKGROUND The pathophysiological changes driving incident kidney cancer remain unclear. This study aimed to identify protein biomarkers and underlying mechanisms using pre-diagnostic plasma proteomics. MATERIALS AND METHODS Among 48,851 UK Biobank participants, 165 were diagnosed… read more here.
Keywords: cancer; risk; kidney cancer; plasma proteomics ... See more keywords
Feasibility of plasma proteomics in patients with immune thrombocytopenia
Sign Up to like & getrecommendations! Published in 2024 at "British Journal of Haematology"
DOI: 10.1111/bjh.19882
Abstract: ITP is an acquired autoimmune bleeding disorder characterized by an isolated thrombocytopenia. The pathophysiology is highly multifactorial and involves antibody‐ and/or cytotoxic T cell‐mediated killing of platelets and disruption of megakaryocyte function hampering platelet production.… read more here.
Keywords: feasibility plasma; patients immune; immune thrombocytopenia; plasma proteomics ... See more keywords
Prioritizing Candidates of Post–Myocardial Infarction Heart Failure Using Plasma Proteomics and Single-Cell Transcriptomics
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circulationaha.119.045158
Abstract: Supplemental Digital Content is available in the text. Background: Heart failure (HF) is the most common long-term complication of acute myocardial infarction (MI). Understanding plasma proteins associated with post-MI HF and their gene expression may… read more here.
Keywords: post; plasma proteins; cell; single cell ... See more keywords
Is Plasma Proteomics Able to Provide Alternative Paths to Better Understand Hypertension?
Sign Up to like & getrecommendations! Published in 2017 at "Hypertension"
DOI: 10.1161/hypertensionaha.117.09049
Abstract: See related article, pp 412–419 The history of hypertension research is sweet sour. Huge advances have been marred by the persistence of huge black boxes. The term primary hypertension epitomizes the issue: the underlying causes… read more here.
Keywords: hypertension plasma; able provide; plasma proteomics; proteomics able ... See more keywords