Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma – Contributions of platelet extracellular vesicles in plasma samples
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12213
Abstract: Abstract Background: The ability to isolate extracellular vesicles (EVs) from blood is vital in the development of EVs as disease biomarkers. Both serum and plasma can be used, but few studies have compared these sources… read more here.
Keywords: extracellular vesicles; serum; serum plasma; evs ... See more keywords
Method development and validation for simultaneous determination of six tyrosine kinase inhibitors and two active metabolites in human plasma/serum using UPLC-MS/MS for therapeutic drug monitoring.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114562
Abstract: Over the past decades, therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKIs) and their main active metabolites has shown benefits in improving treatment efficacy and safety. Therefore, a sensitive, simple and economical ultrahigh-performance liquid… read more here.
Keywords: therapeutic drug; drug monitoring; active metabolites; plasma serum ... See more keywords
Simultaneous quantification of progestogens in plasma and serum by UHPLC-HRMS employing multiplexed targeted single ion monitoring.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122358
Abstract: Progesterone is the predominant gestagen in most mammals studied so far. It plays a substantial role in the regulation of the female reproductive cycle and in providing support for pregnancy maintenance. Despite its known functions,… read more here.
Keywords: thp; plasma serum; uhplc hrms; dhp dhp ... See more keywords
Deep-Dive Targeted Quantification for Ultrasensitive Analysis of Proteins in Nondepleted Human Blood Plasma/Serum and Tissues.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b01878
Abstract: Mass spectrometry-based targeted proteomics (e.g., selected reaction monitoring, SRM) is emerging as an attractive alternative to immunoassays for protein quantification. Recently we have made significant progress in SRM sensitivity for enabling quantification of low nanograms… read more here.
Keywords: quantification; plasma serum; blood plasma;
Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.0c00537
Abstract: Quantitative nuclear magnetic resonance (NMR) spectroscopy of blood plasma is widely used to investigate perturbed metabolic processes in human diseases. The reliability of biochemical data derived from these measurements is dependent on the quality of… read more here.
Keywords: plasma serum; nmr spectroscopy; blood; spectroscopy ... See more keywords
High Throughput LC-MS Platform for Large Scale Screening of Bioactive Polar Lipids in Human Plasma and Serum
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.2c00297
Abstract: Lipids play a key role in many biological processes, and their accurate measurement is critical to unraveling the biology of diseases and human health. A high throughput HILIC-based (LC-MS) method for the semiquantitative screening of… read more here.
Keywords: human plasma; throughput platform; high throughput; mrm transitions ... See more keywords
Malondialdehyde-Induced Post-Translational Modification of Human Hemoglobin.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00764
Abstract: Lysine residues in proteins undergo multiple enzymatic and nonenzymatic post-translational modifications (PTMs). The terminal ε amine group of lysine residues in proteins is carbonylated chemically by carbonyl species such as glyoxal (GO; OCH–CHO, C2H2O2; MW… read more here.
Keywords: mda; malondialdehyde induced; post translational; plasma serum ... See more keywords
Cell-free DNA from human plasma and serum differs in content of telomeric sequences and its ability to promote immune response
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-02905-8
Abstract: Circulating cell-free DNA (cfDNA) may be involved in immune response regulation. We studied the variations in abundance of telomeric sequences in plasma and serum in young healthy volunteers and the ability of cfDNA contained in… read more here.
Keywords: cell free; serum; telomeric sequences; immune response ... See more keywords
Fully automated rapid quantification of Hepatitis C Virus RNA in human plasma and serum by integrated on-chip RT-qPCR and capillary electrophoresis
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64169-z
Abstract: The quantification of hepatitis C virus (HCV) is essential for the management of chronic hepatitis C therapy. We have developed a fully automated microfluidic RT-qPCR system for rapid quantitative detection of HCV RNA in human… read more here.
Keywords: plasma serum; quantification; hcv; fully automated ... See more keywords
PSVII-14 Toxic and essential elements in seminal plasma and serum in stallions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Animal Science"
DOI: 10.1093/jas/skz258.626
Abstract: The aim of the work was compare the concentration the of toxic and essential elements in the sperm plasma and blood serum of stallions. Sperm plasma and serum were collected from 39 Arabian stallions, aged… read more here.
Keywords: toxic essential; serum; sperm plasma; plasma serum ... See more keywords
Clozapine and Norclozapine Concentrations in Paired Human Plasma and Serum Samples
Sign Up to like & getrecommendations! Published in 2018 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000000478
Abstract: Background: Plasma and serum are often used interchangeably for therapeutic drug monitoring (TDM) purposes, and concentrations of some drugs are reported to be lower in serum than in plasma when collected into blood collection tubes… read more here.
Keywords: plasma; clozapine norclozapine; serum; blood ... See more keywords