Dried plasma spot-based liquid chromatography-tandem mass spectrometry for the quantification of methotrexate in human plasma and its application in therapeutic drug monitoring.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202100700
Abstract: Methotrexate, a folic acid antitumor drug, is widely used to treat childhood acute lymphoblastic leukemia. Therapeutic drug monitoring is crucial for adjusting the dosage of methotrexate according to its plasma concentration and reducing adverse effects.… read more here.
Keywords: spot; plasma spot; methotrexate; dried plasma ... See more keywords
Dried plasma spot assay for sunitinib and its active metabolite by high performance liquid chromatography tandem mass spectrometry: 547P
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Oncology"
DOI: 10.1093/annonc/mdx678.004
Abstract: plasma protein-A (PAPP-A) is a metalloproteinase that cleaves insulin-like growth factor 1 (IGF-1) from a circulating complex formed with insulin-like growth factor binding protein 4 (IGFBP4). Increased bioavailability of IGF1 subsequently impacts on tumour biology.… read more here.
Keywords: active metabolite; dried plasma; sunitinib active; plasma spot ... See more keywords
Diagnostic accuracy of dried plasma spot specimens for HIV-1 viral load testing: a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of acquired immune deficiency syndromes"
DOI: 10.1097/qai.0000000000002855
Abstract: BACKGROUND Dried plasma spot specimens may be a viable alternative to traditional liquid plasma in field settings, but the diagnostic accuracy is not well understood. METHODS Standard databases (PubMed and Medline), conferences, and grey literature… read more here.
Keywords: dried plasma; diagnostic accuracy; viral load; spot specimens ... See more keywords
Non-Lethal Blood Sampling of Fish in the lab and Field With Methods for Dried Blood Plasma Spot Omic Analyses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.795348
Abstract: There is global acknowledgment that humane methods in animal research are a priority, but few environmental effects monitoring programs use nonlethal methods for fish. The goal of the present study was to determine the impacts… read more here.
Keywords: blood sampling; plasma spot; non lethal; dried blood ... See more keywords
Dried Plasma Spot Based LC–MS/MS Method for Monitoring of Meropenem in the Blood of Treated Patients
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27061991
Abstract: Meropenem (MER) is widely used to treat complicated and serious infections. Therapeutic drug monitoring (TDM) provides a valid clinical tool to avoid suboptimal concentrations and dose–related adverse reactions. However, TDM seems to face challenges since… read more here.
Keywords: plasma spot; dried plasma; plasma; method ... See more keywords