Simultaneous Determination of Vancomycin and Creatinine by Dried Plasma Spotsampling via LC-MS/MS.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of separation science"
DOI: 10.1002/jssc.70279
Abstract: Routine monitoring of vancomycin drug concentrations is crucial for optimizing dosages to ensure therapeutic efficacy and minimize adverse effects. Vancomycin's clearance is highly correlated with creatinine clearance. However, in developing countries, the majority of hospitals… read more here.
Keywords: creatinine dried; dried plasma; vancomycin creatinine; simultaneous determination ... See more keywords
Dried plasma spots for therapeutic monitoring of amikacin: Validation of an UHPLC-MS/MS assay and pharmacokinetic application.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113201
Abstract: Amikacin (AMI) is an aminoglycoside antibiotic widely used in the treatment of severe infections caused by multi-resistant bacteria, with established exposition targets in therapeutic drug monitoring (TDM). The usual specimen for AMI concentration measurement is… read more here.
Keywords: dried plasma; plasma spots; spots therapeutic; ami ... See more keywords
Quantification of Zonisamide in Dried Blood Spots and Dried Plasma Spots by UPLC–MS/MS: Application to Clinical Practice
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DOI: 10.3390/molecules27154899
Abstract: In this research, a UHPLC–MS/MS method was developed and validated for the determination of zonisamide in dried plasma spots (DPS) and dried blood spots (DBS). Detection of zonisamide and internal standard, 1-(2,3-dichlorphenyl)piperazine, was carried out… read more here.
Keywords: zonisamide; dried plasma; dried blood; blood ... See more keywords