Analysis of circulating tumour DNA in paired plasma and sputum samples of EGFR-mutated NSCLC patients
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz257.012
Abstract: Abstract Background Liquid biopsy is a minimally invasive strategy to detect genetic alterations in non-small cell lung cancer (NSCLC) patients. In particular, it is clinically useful for the detection of the EGFR T790M resistance mutation… read more here.
Keywords: egfr mutated; sputum; plasma sputum; nsclc patients ... See more keywords
Quantitative Method for the Analysis of Ivacaftor, Hydroxymethyl Ivacaftor, Ivacaftor Carboxylate, Lumacaftor, and Tezacaftor in Plasma and Sputum Using Liquid Chromatography With Tandem Mass Spectrometry and Its Clinical Applicability
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DOI: 10.1097/ftd.0000000000000829
Abstract: Background: The novel cystic fibrosis transmembrane conductance regulator (CFTR) modulators, ivacaftor, lumacaftor, and tezacaftor, are the first drugs directly targeting the underlying pathophysiological mechanism in cystic fibrosis (CF); however, independent studies describing their pharmacokinetics are… read more here.
Keywords: lumacaftor tezacaftor; method; ivacaftor; plasma sputum ... See more keywords
Pharmacokinetic/pharmacodynamic analysis of high‐dose tigecycline, by Monte Carlo simulation, in plasma and sputum of patients with hospital‐acquired pneumonia
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DOI: 10.1111/jcpt.13823
Abstract: To Investigate the pharmacokinetic/pharmacodynamic (PK/PD) parameters of high‐dose tigecycline in plasma and sputum of patients with hospital‐acquired pneumonia (HAP), and provide a therapeutic regimen of multidrug‐resistant bacteria (MDRB) infections. read more here.
Keywords: plasma sputum; sputum patients; pharmacokinetic pharmacodynamic; patients hospital ... See more keywords