Plasma triglycerides as a risk factor for chronic kidney disease in type 2 diabetes mellitus: Evidence from northeastern Thailand.
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2018.02.011
Abstract: AIMS To investigate the observational association between plasma triglyceride and CKD in patients with T2DM. METHODS A hospital-based retrospective registry was used to obtain data of 3,748 T2DM patients from May 2016 to October 2016.… read more here.
Keywords: t2dm patients; plasma; plasma triglycerides; ckd ... See more keywords
Intermittent chylomicronemia caused by intermittent GPIHBP1 autoantibodies.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2020.01.012
Abstract: Chylomicronemia caused by a deficiency in lipoprotein lipase (LPL) or GPIHBP1 (the endothelial cell protein that transports LPL to the capillary lumen) is typically diagnosed during childhood and represents a serious, lifelong medical problem. Affected… read more here.
Keywords: chylomicronemia caused; triglyceride levels; gpihbp1 autoantibodies; plasma triglyceride ... See more keywords
Metabolism of triglyceride-rich lipoproteins in health and dyslipidaemia
Sign Up to like & getrecommendations! Published in 2022 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-022-00676-y
Abstract: Accumulating evidence points to the causal role of triglyceride-rich lipoproteins and their cholesterol-enriched remnants in atherogenesis. Genetic studies in particular have not only revealed a relationship between plasma triglyceride levels and the risk of atherosclerotic… read more here.
Keywords: plasma triglyceride; triglyceride rich; disease; triglyceride ... See more keywords
Regulation of plasma triglyceride partitioning by adipose-derived ANGPTL4 in mice
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-87020-5
Abstract: Elevated plasma triglyceride levels are associated with metabolic disease. Angiopoietin-like protein 4 (ANGPTL4) regulates plasma triglyceride levels by inhibiting lipoprotein lipase (LPL). Our aim was to investigate the role of adipocyte-specific deficiency of ANGPTL4 in… read more here.
Keywords: plasma triglyceride; triglyceride levels; high fat; angptl4 mice ... See more keywords
Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure[S]
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m083832
Abstract: Glycosylphosphatidylinositol-anchored high density lipoprotein–binding protein 1 (GPIHBP1), an endothelial cell protein, binds LPL in the subendothelial spaces and transports it to the capillary lumen. In Gpihbp1−/− mice, LPL remains stranded in the subendothelial spaces, causing… read more here.
Keywords: plasma triglyceride; triglyceride levels; mice; cold exposure ... See more keywords
Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0192740
Abstract: Hyperlipidemia is a risk factor of arteriosclerosis, stroke, and other coronary heart disease, which has been shown to correlate with single nucleotide polymorphisms of genes essential for lipid metabolism, such as lipoprotein lipase (LPL) and… read more here.
Keywords: knock mice; magnolol; mice; plasma triglyceride ... See more keywords
Plasma Triglyceride Levels May Be Modulated by Gene Expression of IQCJ, NXPH1, PHF17 and MYB in Humans
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18020257
Abstract: A genome-wide association study (GWAS) by our group identified loci associated with the plasma triglyceride (TG) response to ω-3 fatty acid (FA) supplementation in IQCJ, NXPH1, PHF17 and MYB. Our aim is to investigate potential… read more here.
Keywords: nxph1 phf17; iqcj nxph1; expression; iqcj ... See more keywords
Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.80560
Abstract: Background: Causality between plasma triglyceride (TG) levels and atherosclerotic cardiovascular disease (ASCVD) risk remains controversial despite more than four decades of study and two recent landmark trials, STRENGTH, and REDUCE-IT. Further unclear is the association… read more here.
Keywords: disease; plasma levels; plasma triglyceride; phenome wide ... See more keywords