Near-infrared light responsive dendrimers facilitate the extraction of bicalutamide from human plasma and urine.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology journal"
DOI: 10.1002/biot.202100299
Abstract: BACKGROUND Today, it is well accepted that the quantitative measurement of anti-cancer drugs in human biological samples requires the development and validation of efficient bioanalytical methods. This study attempts to provide a high-capacity and thermo-sensitive… read more here.
Keywords: extraction; plasma urine; light responsive; near infrared ... See more keywords
A single LC‐MS/MS validated method for tulathromycin quantification in plasma, seminal plasma, and urine to be applied in a pharmacokinetic study in bull
Sign Up to like & getrecommendations! Published in 2022 at "Drug Testing and Analysis"
DOI: 10.1002/dta.3270
Abstract: Abstract Tulathromycin is a macrolide antibiotic generally used for the treatment of respiratory diseases in cattle and swine. This work proposes an improvement of a previously published LC‐MS/MS method for tulathromycin determination in pig serum,… read more here.
Keywords: pharmacokinetic study; plasma seminal; method tulathromycin; plasma urine ... See more keywords
Capillary electrophoresis coupled with chloroform‐acetonitrile extraction for rapid and highly selective determination of cysteine and homocysteine levels in human blood plasma and urine
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700133
Abstract: A rapid and selective method has been developed for highly sensitive determination of total cysteine and homocysteine levels in human blood plasma and urine by capillary electrophoresis (CE) coupled with liquid–liquid extraction. Analytes were first… read more here.
Keywords: extraction; plasma urine; homocysteine; human blood ... See more keywords
Integrated analysis of plasma and urine reveals unique metabolomic profiles in idiopathic inflammatory myopathies subtypes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13045
Abstract: Idiopathic inflammatory myopathies (IIM) are a class of autoimmune diseases with high heterogeneity that can be divided into different subtypes based on clinical manifestations and myositis‐specific autoantibodies (MSAs). However, even in each IIM subtype, the… read more here.
Keywords: analysis plasma; idiopathic inflammatory; plasma urine; urine reveals ... See more keywords
Abnormalities in metabolic pathways in celiac disease investigated by the metabolic profiling of small intestinal mucosa, blood plasma and urine by NMR spectroscopy
Sign Up to like & getrecommendations! Published in 2020 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4305
Abstract: Celiac disease (CeD) is an autoimmune enteropathy caused by gluten intake in genetically predisposed individuals. We investigated the metabolism of CeD by metabolic profiling of intestinal mucosa, blood plasma and urine using NMR spectroscopy and… read more here.
Keywords: plasma urine; intestinal mucosa; spectroscopy; mucosa blood ... See more keywords
A sensitive HPLC-MS/MS method for the detection, resolution and quantitation of cathinone enantiomers in horse blood plasma and urine
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03182-1
Abstract: Resolution of cathinone enantiomers in equine anti-doping analysis is becoming more important to distinguish the inadvertent ingestion of plant-based products from those of deliberate administration of designer synthetic analogs. With this in mind, a rapid… read more here.
Keywords: detection; plasma urine; cathinone enantiomers; cathinone ... See more keywords
Evaluating Ga-68 Peptide Conjugates for Targeting VPAC Receptors: Stability and Pharmacokinetics
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-018-1207-x
Abstract: PurposeIn recent years, considerable progress has been made in the use of gallium-68 labeled receptor-specific peptides for imaging oncologic diseases. The objective was to examine the stability and pharmacokinetics of [68Ga]NODAGA and DOTA-peptide conjugate targeting… read more here.
Keywords: peptide; plasma urine; nodaga peptide; dota peptide ... See more keywords
Migration from RIA to LC-MS/MS for aldosterone determination: Implications for clinical practice and determination of plasma and urine reference range intervals in a cohort of healthy Belgian subjects
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Mass Spectrometry"
DOI: 10.1016/j.clinms.2018.06.002
Abstract: Abstract Background Aldosterone measurement is critical for diagnosis of primary aldosteronism and disorders of the renin-angiotensin system. We developed an LC-MS/MS method for plasma and urinary aldosterone and compared it to our RIA method. We… read more here.
Keywords: plasma urine; reference interval; aldosterone; determination ... See more keywords
EGFR mutation testing on plasma and urine samples: A pilot study evaluating the value of liquid biopsy in lung cancer diagnosis and management.
Sign Up to like & getrecommendations! Published in 2021 at "Current problems in cancer"
DOI: 10.1016/j.currproblcancer.2021.100722
Abstract: BACKGROUND Cell free DNA (cfDNA) shed by cancer cells into blood and body fluids is a potential substrate for molecular testing. While plasma is approved for EGFR mutation testing in certain clinical settings, mutation testing… read more here.
Keywords: egfr mutation; plasma urine; group; cancer ... See more keywords
A high‐performance liquid chromatography‐tandem mass spectrometry method for the determination of lifrafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and urine and its application in clinical pharmacokinetic study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.12.038
Abstract: &NA; Lifirafenib (BGB‐283), a dual inhibitor trageting BRAF kinase and EGFR, showed favorable efficacy and safety in treating patients with different cancer types harboring mutations in BRAF, KRAS and NRAS. In order to support the… read more here.
Keywords: clinical pharmacokinetic; plasma; pharmacokinetic study; plasma urine ... See more keywords
Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.06.043
Abstract: Sensitive and comprehensive measurement of systemic metabolites of tryptophan, phenylalanine and glutamate metabolism in biological samples is effective for understanding the pathogenesis of depression and other neurological diseases. Therefore, this study developed an underivatized liquid… read more here.
Keywords: hippocampus; plasma urine; hippocampus plasma; acid ... See more keywords