Plasmid Interactions Can Improve Plasmid Persistence in Bacterial Populations
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.02033
Abstract: It is difficult to understand plasmid maintenance in the absence of selection and theoretical models predict the conditions for plasmid persistence to be limited. Plasmid-associated fitness costs decrease bacterial competitivity, while imperfect partition allows the… read more here.
Keywords: plasmid maintenance; persistence; persistence bacterial; plasmid persistence ... See more keywords
Plasmid Costs Explain Plasmid Maintenance, Irrespective of the Nature of Compensatory Mutations
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12050841
Abstract: Conjugative plasmids often carry virulence and antibiotic-resistant genes. Therefore, understanding the behavior of these extra-chromosomal DNA elements gives insights into their spread. Bacteria frequently replicate slower after plasmids’ entry, an observation inconsistent with the plasmids’… read more here.
Keywords: plasmid costs; plasmid maintenance; compensatory mutations; costs explain ... See more keywords