Recent progress on elucidating the molecular mechanism of plasmid-mediated colistin resistance and drug design
Sign Up to like & getrecommendations! Published in 2019 at "International Microbiology"
DOI: 10.1007/s10123-019-00112-1
Abstract: Antibiotic resistance is a growing global challenge to public health. Polymyxin is considered to be the last-resort antibiotic against most gram-negative bacteria. Recently, discoveries of a plasmid-mediated, transferable mobilized polymyxin resistance gene ( mcr-1 )… read more here.
Keywords: mechanism; drug design; drug; plasmid mediated ... See more keywords
First detection of the plasmid-mediated colistin resistance gene mcr-1 in virulent Vibrio parahaemolyticus.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of food microbiology"
DOI: 10.1016/j.ijfoodmicro.2019.108290
Abstract: The plasmid-mediated colistin resistance gene mcr-1 has been identified in various Enterobacteriaceae species, which poses a great challenge to the public health. The present study aimed to investigate the prevalence of mcr-1 in Vibrio parahaemolyticus… read more here.
Keywords: parahaemolyticus; gene; plasmid mediated; colistin resistance ... See more keywords
Plasmid-mediated colistin resistance in Escherichia coli recovered from healthy poultry.
Sign Up to like & getrecommendations! Published in 2017 at "Revista Argentina de microbiologia"
DOI: 10.1016/j.ram.2017.02.001
Abstract: Fil: Dominguez, Johana Elizabeth. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay; Argentina. Instituto Nacional de Tecnologia Agropecuaria. Centro de Investigacion en Ciencias Veterinarias y Agronomicas. Instituto de Patobiologia; Argentina read more here.
Keywords: escherichia coli; coli recovered; resistance escherichia; colistin resistance ... See more keywords
Detection of plasmid-mediated quinolone resistance in clinical isolates of Enterobacteriaceae strains in Hamadan, West of Iran
Sign Up to like & getrecommendations! Published in 2018 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2016.11.019
Abstract: Plasmid mediated quinolone resistance (PMQR) determinants have arisen as a significant concern in recent years. The aim of this study was screening of resistant-clinical isolates to fluoroquinolone antibiotics and detection of qnr and aac(6′)-Ib-cr genes.… read more here.
Keywords: mediated quinolone; hamadan west; plasmid mediated; quinolone resistance ... See more keywords
Public health implications of plasmid-mediated quinolone and aminoglycoside resistance genes in Escherichia coli inhabiting a major anthropogenic river of India
Sign Up to like & getrecommendations! Published in 2022 at "Epidemiology and Infection"
DOI: 10.1017/s095026882200053x
Abstract: Abstract Presence of antimicrobial resistance (AMR) genes in Escherichia coli inhabiting anthropogenic rivers is an important public health concern because plasmid-mediated AMR genes can easily spread to other pathogens by horizontal gene transfer. Besides β-lactams,… read more here.
Keywords: genes escherichia; plasmid mediated; resistance; amr genes ... See more keywords
Bisphenols Promote the Pheromone-Responsive Plasmid-Mediated Conjugative Transfer of Antibiotic Resistance Genes in Enterococcus faecalis.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c05349
Abstract: The enrichment and spread of antibiotic resistance genes (ARGs) induced by environmental chemical pollution further exacerbated the threat to human health and ecological safety. Several compounds are known to induce R plasmid-mediated conjugation through inducing… read more here.
Keywords: antibiotic resistance; plasmid; plasmid mediated; pheromone responsive ... See more keywords
Bacterial plasmid-mediated quinolone resistance genes in aquatic environments in China
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40610
Abstract: Emerging antimicrobial resistance is a major threat to human’s health in the 21st century. Understanding and combating this issue requires a full and unbiased assessment of the current status on the prevalence of antimicrobial resistance… read more here.
Keywords: plasmid mediated; antimicrobial resistance; resistance; aquatic environments ... See more keywords
Imported food and feed as contributors to the introduction of plasmid‐mediated colistin‐resistant Enterobacteriaceae to a ‘low prevalence’ country
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx161
Abstract: Sir, In the last year, it has become evident that the plasmid-located colistin resistance gene mcr-1 has a worldwide distribution. Colistin is widely used in veterinary medicine, particularly in pigs and poultry, and the selection… read more here.
Keywords: colistin; mcr positive; plasmid mediated; resistance ... See more keywords
Novel plasmid-mediated colistin resistance gene mcr-7.1 in Klebsiella pneumoniae
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dky111
Abstract: Objectives To identify a novel plasmid-mediated colistin resistance gene in Klebsiella pneumoniae isolated from chickens in China. Methods WGS was used to identify a novel colistin resistance gene. The transferability of plasmids carrying mcr-7.1 was… read more here.
Keywords: resistance gene; colistin resistance; plasmid mediated; gene ... See more keywords
Community Origins and Regional Differences Highlight Risk of Plasmid-mediated Fluoroquinolone Resistant Enterobacteriaceae Infections in Children.
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Infectious Disease Journal"
DOI: 10.1097/inf.0000000000002205
Abstract: BACKGROUND Fluoroquinolones are uncommonly prescribed in children, yet pediatric multidrug resistant (MDR) enterobacteriaceae (Ent) infections often reveal fluoroquinolone resistance (FQR). We sought to define the molecular epidemiology of FQR and MDR-Ent in children. METHODS A… read more here.
Keywords: community; plasmid mediated; enterobacteriaceae; ent infections ... See more keywords
Systematic research to overcome newly emerged multidrug‐resistant bacteria
Sign Up to like & getrecommendations! Published in 2020 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12781
Abstract: In the 1980s, I found that the chromosomal β‐lactamase of Klebsiella pneumoniae LEN‐1 showed a very high similarity to the R‐plasmid‐mediated penicillinase TEM‐1 on the amino acid sequence level, and this strongly suggested the origination… read more here.
Keywords: systematic research; plasmid mediated; research overcome; also first ... See more keywords