Articles with "plasmin" as a keyword



Plasmin Prevents Dystrophic Calcification After Muscle Injury

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Published in 2017 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.2973

Abstract: Extensive or persistent calcium phosphate deposition within soft tissues after severe traumatic injury or major orthopedic surgery can result in pain and loss of joint function. The pathophysiology of soft tissue calcification, including dystrophic calcification… read more here.

Keywords: muscle; plasmin; calcification; bone ... See more keywords

The time course of alpha 2-plasmin inhibitor and plasmin-alpha 2-plasmin inhibitor complex levels in patients with traumatic brain injury

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Published in 2025 at "Acta Neurochirurgica"

DOI: 10.1007/s00701-025-06496-6

Abstract: In its acute phase, traumatic brain injury (TBI) is notable for disturbances in the coagulation/fibrinolysis system. Plasmin, alpha 2-plasmin inhibitor (α2-PI), and their complex (plasmin-α2-PI complex [PIC]) are important components of the coagulation-fibrinolytic system, but… read more here.

Keywords: plasmin inhibitor; plasmin; alpha plasmin; injury ... See more keywords

Plasmin determination based on enzymatic digestion of a β-casein layer at the air/water interface

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Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"

DOI: 10.1016/j.colsurfa.2020.125786

Abstract: Abstract The possibility of enzyme activity determination based on natural substrate digestion at the air/water interface has been investigated through the interaction of a β-casein layer with the protease plasmin. The protein layers were spread… read more here.

Keywords: air water; water interface; water; determination ... See more keywords

Urinary Plasmin(ogen) as a Prognostic Factor for Hypertension

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Published in 2018 at "Kidney International Reports"

DOI: 10.1016/j.ekir.2018.06.007

Abstract: Introduction Plasmin and its precursor, plasminogen, are detectable in urine from patients with glomerular disease. Urinary plasmin(ogen) levels correlate with blood pressure (BP) and may contribute to renal Na+ retention by activating the epithelial Na+… read more here.

Keywords: plasmin; mortality; urinary plasmin; hypertension ... See more keywords

Application of high-resolution ultrasonic spectroscopy for detection of the plasmin activity toward β-casein.

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Published in 2021 at "Food chemistry"

DOI: 10.1016/j.foodchem.2021.129373

Abstract: High-resolution ultrasonic spectroscopy (HR-US) was applied for precise detection of plasmin activity towards β-casein in buffer at pH 7.8 and 37 °C. The evolution of ultrasonic velocity and ultrasonic attenuation measured at 15.5 MHz is related to… read more here.

Keywords: detection; plasmin activity; plasmin; casein ... See more keywords

Browplasminin, a condensed tannin with anti-plasmin activity isolated from an aqueous extract of Brownea grandiceps Jacq. flowers.

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Published in 2017 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2017.01.012

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Following Venezuelan traditional medicine, females with heavy menstrual blood loss (menorrhagia) drink Brownea grandiceps Jacq. flowers (BG) decoctions to reduce the bleeding. In a previous study, we demonstrated that BG aqueous extract (E)… read more here.

Keywords: grandiceps jacq; plasmin activity; plasmin; anti plasmin ... See more keywords

Effect of heat treatment on plasmin activity and bio-functional attributes of Cheddar cheese

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Published in 2020 at "Lwt - Food Science and Technology"

DOI: 10.1016/j.lwt.2019.108924

Abstract: Abstract Plasmin is one of the most important proteolytic enzymes present in cheese. This study envisaged evaluation of the effect of change in heat treatment on plasmin system and consequent effect on formation of antioxidative… read more here.

Keywords: heat treatment; ace inhibitory; plasmin; cheddar cheese ... See more keywords

Streptolysin O accelerates the conversion of plasminogen to plasmin

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-54173-6

Abstract: Streptococcus pyogenes is a human-specific bacterial pathogen that produces several proteins that exploit the plasminogen (PLG)-plasmin (PLM) fibrinolysis system to dismantle blood clots and to facilitate spread and survival within the host. In this study,… read more here.

Keywords: plasminogen; accelerates conversion; mass spectrometry; plasmin ... See more keywords

Evolutionary regulation of human Fas ligand (CD95L) by plasmin in solid cancer immunotherapy

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-60990-0

Abstract: Despite sharing >98% genomic similarity, humans are more likely to develop cancers than our closest living ancestors, the nonhuman primates. Here, we unexpectedly discover that, unlike chimpanzee and other primates, a critical embryonic development, immune… read more here.

Keywords: fasl; plasmin; fas ligand; ligand ... See more keywords
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Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface.

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Published in 2020 at "Gastroenterology"

DOI: 10.1053/j.gastro.2020.06.032

Abstract: BACKGROUND & AIMS The protease plasmin is an important wound healing factor, but it is not clear how it affects gastrointestinal infection-mediated damage, such as that resulting from Clostridioides difficile. We investigated the role of… read more here.

Keywords: spore surface; clostridioides difficile; disease; plasmin ... See more keywords

Truncation of ADAMTS13 by Plasmin Enhances Its Activity in Plasma.

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Published in 2018 at "Thrombosis and haemostasis"

DOI: 10.1055/s-0038-1627460

Abstract: ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) cleaves von Willebrand Factor (VWF) multimers to control their thrombogenicity. The fibrinolytic enzyme plasmin can cleave VWF in a similar manner. However,… read more here.

Keywords: truncation adamts13; plasmin enhances; plasmin; adamts13 plasmin ... See more keywords