Improving our understanding on the clinical role of plasmin-mediated von Willebrand factor degradation
Sign Up to like & getrecommendations! Published in 2024 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000825
Abstract: Purpose of review Von Willebrand factor (VWF) plays a pivotal role in primary hemostasis. A Disintegrin And Metalloproteinase with a ThromboSpondin type 1 motif, member 13 (ADAMTS13) is primarily responsible for cleaving ultra-large VWF multimers… read more here.
Keywords: plasmin mediated; role; vwf; plasmin ... See more keywords
A mathematical model of plasmin-mediated fibrinolysis of single fibrin fibers
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DOI: 10.1371/journal.pcbi.1012684
Abstract: Fibrinolysis, the plasmin-mediated degradation of the fibrin mesh that stabilizes blood clots, is an important physiological process, and understanding mechanisms underlying lysis is critical for improved stroke treatment. Experimentalists are now able to study lysis… read more here.
Keywords: plasmin mediated; fibrin fibers; model; fibrinolysis ... See more keywords