Integrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques
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DOI: 10.1186/s12936-017-2029-z
Abstract: BackgroundMild to severe anaemia is a common complication of malaria that is caused in part by insufficient erythropoiesis in the bone marrow. This study used systems biology to evaluate the transcriptional and alterations in cell… read more here.
Keywords: plasmodium cynomolgi; erythropoiesis; insufficient erythropoiesis; bone marrow ... See more keywords
Analysis of erythrocyte dynamics in Rhesus macaque monkeys during infection with Plasmodium cynomolgi
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DOI: 10.1186/s12936-018-2560-6
Abstract: BackgroundMalaria is a major mosquito transmitted, blood-borne parasitic disease that afflicts humans. The disease causes anaemia and other clinical complications, which can lead to death. Plasmodium vivax is known for its reticulocyte host cell specificity,… read more here.
Keywords: plasmodium cynomolgi; analysis erythrocyte; cynomolgi; erythrocyte dynamics ... See more keywords
A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi
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DOI: 10.7554/elife.29605
Abstract: Plasmodium liver hypnozoites, which cause disease relapse, are widely considered to be the last barrier towards malaria eradication. The biology of this quiescent form of the parasite is poorly understood which hinders drug discovery. We… read more here.
Keywords: comparative transcriptomic; parasite plasmodium; liver; plasmodium cynomolgi ... See more keywords