Flexible 3D cell-based platforms for the discovery and profiling of novel drugs targeting Plasmodium hepatic infection.
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DOI: 10.1021/acsinfecdis.9b00144
Abstract: The restricted pipeline of drugs targeting the liver stage of Plasmodium infection reflects the scarcity of cell models that mimic the human hepatic phenotype and drug metabolism, as well as Plasmodium hepatic infection. Using stirred-tank… read more here.
Keywords: hepatic infection; drugs targeting; infection; plasmodium hepatic ... See more keywords