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Published in 2020 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.06.012
Abstract: Tumor evolution from a single cell into a malignant, heterogeneous tissue remains poorly understood. Here, we profile single-cell transcriptomes of genetically engineered mouse lung tumors at seven stages, from pre-neoplastic hyperplasia to adenocarcinoma. The diversity…
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Keywords:
plasticity cell;
evolution;
cell state;
high plasticity ... See more keywords