Presynaptic Homeostatic Plasticity Staves off Neurodegenerative Pathophysiology up to a Tipping Point
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DOI: 10.1016/j.neuron.2020.06.013
Abstract: In this issue of Neuron, Orr et al. (2020) identify an evolutionarily conserved mechanism of presynaptic homeostatic plasticity induced by ALS-like motor neuron degeneration, which maintains excitatory potentials until a threshold of synaptic loss is reached.… read more here.
Keywords: homeostatic plasticity; tipping point; plasticity staves; presynaptic homeostatic ... See more keywords