Recapitulation of Neural Crest Specification and EMT via Induction from Neural Plate Border-like Cells
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DOI: 10.1016/j.stemcr.2020.07.023
Abstract: Summary Neural crest cells (NCCs) contribute to several tissues during embryonic development. NCC formation depends on activation of tightly regulated molecular programs at the neural plate border (NPB) region, which initiate NCC specification and epithelial-to-mesenchymal… read more here.
Keywords: emt; neural plate; plate border; neural crest ... See more keywords
Folate Carrier Deficiency Drives Differential Methylation and Enhanced Cellular Potency in the Neural Plate Border
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DOI: 10.3389/fcell.2022.834625
Abstract: The neural plate border (NPB) of vertebrate embryos segregates from the neural and epidermal regions, and it is comprised of an intermingled group of multipotent progenitor cells. Folate is the precursor of S-adenosylmethionine, the main… read more here.
Keywords: methylation; deficiency drives; folate carrier; neural plate ... See more keywords
Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells
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DOI: 10.7554/elife.21620
Abstract: The ‘neural plate border’ of vertebrate embryos contains precursors of neural crest and placode cells, both defining vertebrate characteristics. How these lineages segregate from neural and epidermal fates has been a matter of debate. We… read more here.
Keywords: border cells; analysis; neural plate; plate border ... See more keywords
Single-cell atlas of early chick development reveals gradual segregation of neural crest lineage from the neural plate border during neurulation
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DOI: 10.7554/elife.74464
Abstract: The epiblast of vertebrate embryos is comprised of neural and non-neural ectoderm, with the border territory at their intersection harboring neural crest and cranial placode progenitors. Here, we a generate single-cell atlas of the developing… read more here.
Keywords: neurulation; neural crest; border; neural plate ... See more keywords