Specific MicroRNAs Found in Extracellular Matrix Vesicles Regulate Proliferation and Differentiation in Growth Plate Chondrocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Calcified tissue international"
DOI: 10.1007/s00223-021-00855-y
Abstract: Matrix vesicles (MVs) are extracellular organelles produced by growth plate cartilage cells in a zone-specific manner. MVs are similar in size to exosomes, but they are tethered to the extracellular matrix (ECM) via integrins. Originally… read more here.
Keywords: plate chondrocytes; growth; matrix vesicles; growth plate ... See more keywords
TRPM7 channels mediate spontaneous Ca2+ fluctuations in growth plate chondrocytes that promote bone development
Sign Up to like & getrecommendations! Published in 2019 at "Science Signaling"
DOI: 10.1126/scisignal.aaw4847
Abstract: The ion channel TRPM7 mediates Ca2+ fluctuations in growth plate chondrocytes that are needed for proper bone growth. Ca2+ fluctuations promote growth plate chondrogenesis In the growth plates of long bones, ordered arrays of chondrocytes… read more here.
Keywords: trpm7; growth plate; bone; plate chondrocytes ... See more keywords
Long non-coding RNA Gas5 regulates proliferation and apoptosis in HCS-2/8 cells and growth plate chondrocytes by controlling FGF1 expression via miR-21 regulation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-018-0424-6
Abstract: BackgroundLncRNA Gas5 is known to be a key control element during growth, differentiation and development in mammalian species. However, the role and function of Gas5 in growth plate chondrocytes has not been determined.MethodsThe overexpression and… read more here.
Keywords: growth plate; apoptosis; gas5; plate chondrocytes ... See more keywords
The Effect of Estradiol on the Growth Plate Chondrocytes of Limb and Spine from Postnatal Mice in vitro: The Role of Estrogen-Receptor and Estradiol Concentration
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.17696
Abstract: Objectives: Skeletal development is a complex process. Little is known about the different response of limb or spine growth plate chondrocytes (LGP or SGP) to the estrogen level and the role of estrogen receptor (ER)… read more here.
Keywords: growth plate; estrogen; effect; limb spine ... See more keywords