Evaluation of the Association of Platelet Count, Mean Platelet Volume, and Platelet Transfusion With Intraventricular Hemorrhage and Death Among Preterm Infants
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DOI: 10.1001/jamanetworkopen.2022.37588
Abstract: Key Points Question What are the associations of platelet transfusion, platelet count (PC), and mean platelet volume (MPV) with intraventricular hemorrhage (IVH) and mortality in preterm infants? Findings In this cohort study of 1221 preterm… read more here.
Keywords: count mean; platelet transfusion; preterm infants; platelet ... See more keywords
Annexin V‐Modified Platelet‐Biomimetic Nanomedicine for Targeted Therapy of Acute Ischemic Stroke
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DOI: 10.1002/adhm.202200416
Abstract: Thromboembolic stroke is typically characterized by the activation of platelets, resulting in thrombus in the cerebral vascular system, leading to high morbidity and mortality globally. Intravenous thrombolysis by tissue plasminogen activator (tPA) administration within 4.5… read more here.
Keywords: platelet biomimetic; acute ischemic; platelet; ischemic stroke ... See more keywords
BMI is an important determinant of VWF and FVIII levels and bleeding phenotype in patients with von Willebrand disease
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25499
Abstract: observed during eltrombopag treatment or at the follow-up visits routinely performed 30 days after surgery. As eltrombopag has been associated with occurrence of cataracts in patients with immune thrombocytopenia, and MYH9-RD is a syndromic disorder… read more here.
Keywords: important determinant; determinant vwf; eltrombopag; bmi important ... See more keywords
Platelets from Calreticulin mutated essential thrombocythemia patients are less reactive than JAK2 V617F mutated platelets
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25713
Abstract: Both JAK2V617F and calreticulin (CALR) mutated essential thrombocythemia (ET) patients have different clinical characteristics, with lower thrombosis risk in patients with CALR mutations. To elucidate the mechanism for this lower risk we studied platelet function… read more here.
Keywords: calr mutated; mutated platelets; platelet; mutated essential ... See more keywords
Familial thrombocytopenia flare‐up following the first dose of mRNA‐1273 Covid‐19 vaccine
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26128
Abstract: To the Editor: A 36-year-old female with a past medical history of thrombocytopenia, previously classified as immune thrombocytopenic purpura (ITP), presented to the hospital with diffuse petechiae, easy bruising, bleeding gums and a mild headache.… read more here.
Keywords: thrombocytopenia; covid vaccine; mrna 1273; vaccine ... See more keywords
Iron and platelets: A subtle, under‐recognized relationship
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DOI: 10.1002/ajh.26189
Abstract: The role of iron in the formation and functioning of erythrocytes, and to a lesser degree of white blood cells, is well established, but the relationship between iron and platelets is less documented. Physiologically, iron… read more here.
Keywords: iron platelets; relationship iron; platelets subtle; iron ... See more keywords
Safety of intravenous arginine therapy in children with sickle cell disease hospitalized for vaso‐occlusive pain: A randomized placebo‐controlled trial in progress
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26396
Abstract: 1. Semple JW, Italiano JE, Freedman J. Platelets and the immune continuum. Nat Rev Immunol. 2011;11(4):264-274. 2. Sol N, Wurdinger T. Platelet RNA signatures for the detection of cancer. Cancer Metastasis Rev. 2017;36(2):263-272. 3. Franco… read more here.
Keywords: cancer; platelet; cell; tumor educated ... See more keywords
Form follows function for freeze‐dried platelets
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26460
Abstract: Platelets—essential players in hemostasis—represent major challenges in hematology and transfusion medicine. Demand for platelets remains high in many clinical contexts including hematology-oncology, transplant surgery, cardiac surgery, and trauma medicine. Yet, supply from donors is fragile,… read more here.
Keywords: freeze dried; dried platelets; hematology; platelet ... See more keywords
Evaluation of Platelet Parameters in Children with Autism Spectrum Disorder: Elongated Collagen‐Adenosine Diphosphate and Collagen‐Epinephrine Closure Times
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DOI: 10.1002/aur.2122
Abstract: Changes related to the serotonin system play a key role in the etiology of autism spectrum disorder (ASD). Although we know that platelets are associated with the serotonin system, their relation to ASD has not… read more here.
Keywords: collagen; closure times; autism; disorder ... See more keywords
Impact of low‐dose prasugrel on platelet reactivity and cardiac dysfunction in acute coronary syndrome patients requiring primary drug‐eluting stent implantation: A randomized comparative study
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DOI: 10.1002/ccd.28277
Abstract: The aim of this study was to compare how prasugrel and clopidogrel affect platelet aggregation reactivity, cardiac enzyme release, cardiac remodeling, and the formation of in‐stent thrombi after primary percutaneous coronary intervention (PCI). read more here.
Keywords: low dose; reactivity cardiac; study; impact low ... See more keywords
Platelet mass cytometry: Optimization of sample, reagent, and analysis parameters
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DOI: 10.1002/cyto.a.24300
Abstract: Platelets mediate key biological processes, including hemostasis, immunity, and inflammation. Although platelets are often treated as a homogeneous cell population, they are known to be heterogeneous in size, age, surface receptor expression, and response to… read more here.
Keywords: sample; mass cytometry; analysis; cytometry ... See more keywords