Synthesis, in vitro cytotoxicity and anti-platelet activity of new 1,3-bentzenedisulfonamides
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DOI: 10.1007/s00044-019-02419-0
Abstract: To obtain more active and selective anti-platelet candidate drugs, we tried to introduce a methyl group at the 5-position and 6-position of the parent benzene ring first time, respectively or simultaneously. The idea could inspect… read more here.
Keywords: anti platelet; platelet activity; series; cytotoxicity ... See more keywords
Antiplatelet Medications and Biomarkers of Hemostasis May Explain the Association of Hematoma Appearance and Subsequent Hematoma Expansion After Intracerebral Hemorrhage
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DOI: 10.1007/s12028-021-01369-z
Abstract: To test the hypothesis that appearances of intracranial hematomas on diagnostic computed tomography (CT) are not idiosyncratic and reflect a biologically plausible mechanism, we evaluated the association between hematoma appearance on CT, biomarkers of platelet… read more here.
Keywords: association hematoma; platelet activity; antiplatelet; sign ... See more keywords
Sex differences in platelet reactivity in patients with myocardial infarction treated with triple antiplatelet therapy - results from assessing platelet activity in coronary heart disease (APACHE)
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DOI: 10.1080/09537104.2020.1771550
Abstract: Abstract )Several earlier studies have reported increased risk of bleeding in women with myocardial infarction, (MI) compared to men. The reasons for the observed difference are incompletely understood, but one suggested explanation has been excess… read more here.
Keywords: platelet activity; sex differences; myocardial infarction; platelet ... See more keywords
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis
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DOI: 10.1080/09537104.2022.2042233
Abstract: Abstract MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by induction of mRNA degradation and post-transcriptional repression of gene expression. Platelets are the major source of circulating miRNAs, with significant regulatory potential… read more here.
Keywords: platelet; platelet activity; hsa mir; platelet related ... See more keywords