Inhibitory Effects of 3‐Deoxysappanchalcone on Factor Xa Activity, Platelet Aggregation, and Experimentally Induced Thrombosis
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DOI: 10.1002/ardp.70101
Abstract: 3‐Deoxysappanchalcone (3‐DSC), extracted from Caesalpinia sappan L., is recognized for its anti‐inflammatory, anti‐influenza, and anti‐allergic effects, but its antithrombotic properties have not been investigated. This study explores whether 3‐DSC exhibits antithrombotic effects and examines the… read more here.
Keywords: aggregation; factor activity; platelet aggregation;
Autophagic regulation of platelet biology
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DOI: 10.1002/jcp.28243
Abstract: Platelets, developed from megakaryocytes, are characterized by anucleate and short‐life span hemocyte in mammal vessel. Platelets are very important in the cardiovascular system. Studies indicate the occurrence of autophagy platelets and megakaryocytes. Moreover, abnormal autophagy… read more here.
Keywords: platelet biology; platelet aggregation; biology; autophagic regulation ... See more keywords
A systematic review of randomized controlled trials related to the effects of garlic supplementation on platelet aggregation
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DOI: 10.1002/ptr.7556
Abstract: The increment of platelet aggregation factors has been considered a key phenomenon in atherosclerosis. Studies have shown that garlic (Allium sativum) is associated with a reduction in platelet aggregation and thrombosis. Hence, the present systematic… read more here.
Keywords: aggregation; randomized controlled; controlled trials; systematic review ... See more keywords
Abnormal platelet aggregation in pediatric pulmonary hypertension
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DOI: 10.1002/pul2.12104
Abstract: Abstract Endogenous prostacyclin stimulates pulmonary vasodilation and inhibits platelet aggregation. For the synthetic analog treprostinil, used in the treatment of pulmonary hypertension (PH), conflicting, anecdotal evidence exists regarding its effects on clinically relevant platelet function.… read more here.
Keywords: abnormal platelet; aggregation; pulmonary hypertension; aggregation pediatric ... See more keywords
Synthesis and in vitro activities on anti-platelet aggregation of 4-methoxyisophthalamides
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DOI: 10.1007/s00044-018-2207-8
Abstract: A series of 4-methoxyisophthalamides (1d–1w) were designed and synthesized and their chemical structures were confirmed by IR, MS, 1H-NMR, and 13C-NMR. The in vitro on anti-platelet aggregation activities of these compounds were assessed by using… read more here.
Keywords: platelet aggregation; synthesis vitro; anti platelet; vitro activities ... See more keywords
Hirudins and fenestrins of the African medicinal leech Asiaticobdella fenestrata
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DOI: 10.1007/s00436-025-08578-x
Abstract: African hematophagous leeches are largely underinvestigated both in terms of their biodiversity and the characterization of the repertoire of bioactive components of their salivary gland secretions. Asiaticobdella (formerly Aliolimnatis) fenestrata Moore, 1939, also referred to… read more here.
Keywords: medicinal leech; african medicinal; platelet aggregation; rgd motif ... See more keywords
[Inhibition of platelet aggregation (Update 2019)].
Sign Up to like & getrecommendations! Published in 2019 at "Wiener klinische Wochenschrift"
DOI: 10.1007/s00508-018-1437-6
Abstract: Acute thrombotic complications as a key feature of accelerated atherothrombotic disease typically precipitate cardiovascular events and therefore strongly contribute to cardiovascular morbidity and mortality in diabetic patients. Inhibition of platelet aggregation can reduce the risk for… read more here.
Keywords: platelet aggregation; aggregation update; update 2019; inhibition platelet ... See more keywords
Improvement of platelet aggregation and rapid induction of hemostasis in chitosan dressing using silver nanoparticles
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DOI: 10.1007/s10570-019-02795-1
Abstract: There is an increasing demand for high-performance hemostatic agents with good antibacterial efficiency and biocompatibility. In this study, a chitosan/gelatin/sodium hyaluronate hemostatic dressing with silver nanoparticles (CGSH/Ag50) was designed and characterized. Our results suggest that… read more here.
Keywords: cgsh ag50; silver nanoparticles; improvement platelet; platelet aggregation ... See more keywords
Lebetin Peptides, A New Class of Potent Platelet Aggregation Inhibitors: Chemical Synthesis, Biological Activity and NMR Spectroscopic Study
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DOI: 10.1007/s10989-019-09812-8
Abstract: Platelets have a well-established role in atherosclerosis and related diseases. Lebetins from the venom of Vipera lebetina , lacking the RGD sequence, emerged as a new family of platelet aggregation inhibitors. However, the interaction sites… read more here.
Keywords: platelet aggregation; aggregation inhibitors; platelet; lebetin peptides ... See more keywords
Characterization of core/shell Cu/Ag nanopowders synthesized by electrochemistry and assessment of their impact on hemolysis, platelet aggregation, and coagulation on human blood for potential wound dressing use
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DOI: 10.1007/s11051-017-3937-0
Abstract: Copper/silver core/shell nanopowders with different metal ratio have been elaborated by electrochemistry (ultrasound-assisted electrolysis followed by a displacement reaction). Characterization was performed by several methods (X-ray diffraction, scanning electron microscope, energy-dispersive X-ray spectroscopy, transmission electron… read more here.
Keywords: platelet aggregation; spectroscopy; hemolysis; electrochemistry ... See more keywords
First evidence: rivaroxaban and apixaban reduce thrombin-dependent platelet aggregation
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DOI: 10.1007/s11239-018-1709-z
Abstract: Rivaroxaban and apixaban are direct oral anticoagulants whose target specificity is to activate factor X (FXa). It is still not fully understood how xabans impact platelet function. This single-center observational study aimed to assess in… read more here.
Keywords: platelet aggregation; rivaroxaban apixaban; platelet; first evidence ... See more keywords