Articles with "platelet antigen" as a keyword



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Human platelet antigen 1, 2 and 5 gene polymorphisms in Egyptians and their potential association with susceptibility to immune thrombocytopenic purpura in Egyptian patients

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Published in 2018 at "Hematology"

DOI: 10.1080/10245332.2017.1365435

Abstract: ABSTRACT Objectives: This study determined the incidence of HPA1, HPA2 and HPA5 polymorphisms in 120 Egyptian immune thrombocytopenic purpura (ITP) patients and 120 healthy Egyptian subjects. Methods: Human platelet antigen (HPA) genotyping was done using… read more here.

Keywords: frequency; platelet antigen; immune thrombocytopenic; human platelet ... See more keywords
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Current understanding and future perspectives for anti‐human platelet antigen‐15 antibodies in patients with alloimmune thrombocytopenia: History, laboratory testing, and clinical impact

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Published in 2022 at "Transfusion"

DOI: 10.1111/trf.16845

Abstract: Alloantibodies against human platelet antigen (HPA) are pathogenic agents involved in the development of several alloimmune thrombocytopenias, such as fetal and neonatal thrombocytopenia (FNAIT), platelet transfusion refractoriness (PTR), and post-transfusion purpura (PTP). To date, the… read more here.

Keywords: platelet antigen; current understanding; human platelet; hpa ... See more keywords
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A first WHO reference reagent for the detection of anti-human platelet antigen-15b.

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Published in 2021 at "Vox sanguinis"

DOI: 10.1111/vox.13167

Abstract: BACKGROUND AND OBJECTIVES Alloantibodies to human platelet antigen-15b (anti-HPA-15b) have been detected in mothers with foetal-neonatal alloimmune thrombocytopenia and in multiply transfused patients. Assays used to detect this antibody, which aids in disease diagnosis, can… read more here.

Keywords: anti hpa; platelet antigen; reference reagent; platelet ... See more keywords