Mechanistic insight of platelet apoptosis leading to non-surgical bleeding among heart failure patients supported by continuous-flow left ventricular assist devices
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DOI: 10.1007/s11010-017-3021-1
Abstract: Non-surgical bleeding (NSB) is the most common clinical complication in heart failure (HF) patients supported by continuous-flow left ventricular assist devices (CF-LVADs). In this study, oxidative stress and alteration of signal pathways leading to platelet… read more here.
Keywords: platelet; bleeder group; platelet apoptosis;
Flow cytometry identifies an early stage of platelet apoptosis produced by agonists of the P2X1 and P2X7 receptors
Sign Up to like & getrecommendations! Published in 2022 at "Platelets"
DOI: 10.1080/09537104.2021.1981844
Abstract: Abstract Platelets express P2X1 receptors and our data also show the expression of P2X7 receptors. We studied the role of both receptors in platelet apoptosis by incubation of PRP with P2X agonists, then centrifuged to… read more here.
Keywords: platelet apoptosis; p2x7 receptors; apoptosis; early stage ... See more keywords
Mitochondrial Inner Membrane Depolarization as a Marker of Platelet Apoptosis
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Applied Thrombosis/Hemostasis"
DOI: 10.1177/1076029616665924
Abstract: Availability of universal marker for the diagnosis of platelet apoptosis is an important but currently unresolved goal of platelet physiology investigations. Mitochondrial inner transmembrane potential (▵Ψm) depolarization is frequently used as a marker of apoptosis… read more here.
Keywords: apoptosis; platelet apoptosis; marker platelet; marker ... See more keywords
Apoptosis in platelets is independent of the actin cytoskeleton
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DOI: 10.1371/journal.pone.0276584
Abstract: Homeostasis between platelet production and clearance is essential for human health. A critical facet of the balance that facilitates platelet clearance from the circulation is apoptosis (programmed cell death). The precise cellular mechanisms that underpin… read more here.
Keywords: platelet apoptosis; apoptosis platelets; actin cytoskeleton; abt 737 ... See more keywords
Investigation of Platelet Apoptosis in Patients after Surgical Myocardial Revascularization
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DOI: 10.3390/biomedicines11020251
Abstract: Platelets are one of the main participants in vascular accidents in cases of coronary heart disease (CHD). In this study, we sought to detect platelet apoptosis in patients with coronary artery disease who underwent scheduled… read more here.
Keywords: platelet apoptosis; surgery; myocardial revascularization; revascularization ... See more keywords