Impact of Variable Recombinant Factor VIII Binding on Platelet Functions
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DOI: 10.1182/blood-2024-193865
Abstract: Introduction: Hemophilia A (HA) is a rare genetic bleeding disorder caused by a deficiency of functional coagulation factor VIII (FVIII). Platelets have important functions throughout the various stages of hemostasis. Upon injury, platelets become activated… read more here.
Keywords: rfviii; shift; pro aggregatory; platelet binding ... See more keywords
Sialofucosylation Enables Platelet Binding to Myeloma Cells via P-Selectin and Suppresses NK Cell-Mediated Cytotoxicity
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DOI: 10.3390/cancers15072154
Abstract: Simple Summary Platelet cloaking of tumor cells has been shown to play an important role in tumor metastasis and immune evasion. Multiple myeloma is a tumor of the plasma cells that colonizes different sites of… read more here.
Keywords: platelet binding; myeloma; myeloma cells; mediated cytotoxicity ... See more keywords