Effects of Glycosaminoglycan from Urechis unicinctus on ADP-Induced Platelet Calcium and Membrane Glycoprotein Expressions in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Acta Haematologica"
DOI: 10.1159/000505769
Abstract: Background: Previous studies had shown that glycosaminoglycan (GAG) from Urechis unicinctus exerts an obvious antiplatelet aggregation effect. Objective: This study aims to investigate the effects of GAG from Urechis unicinctus on ADP-induced platelet calcium and… read more here.
Keywords: urechis unicinctus; platelet calcium; adp induced; membrane ... See more keywords
Multiscale simulations that incorporate patient-specific neural network models of platelet calcium signaling predict diverse thrombotic outcomes under flow
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1013085
Abstract: During thrombosis, platelets rapidly deposit and activate on the vessel wall, driving conditions such as myocardial infarction and stroke. The complexity of thrombus formation in pathological flow geometries, along with patient-specific pharmacological responses, presents an… read more here.
Keywords: patient specific; platelet calcium; multiscale simulations; simulations incorporate ... See more keywords