Activation of Platelet NLRP3 Inflammasome in Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.705325
Abstract: Patients with Crohn’s disease (CD) are inclined to have platelet hyperactivity and an increased risk of intestinal micro-thrombosis. However, the mechanisms underlying platelet hyperactivity in CD are not well understood. We investigated the assembly of… read more here.
Keywords: patients active; platelet nlrp3; nlrp3 inflammasome; platelet hyperactivity ... See more keywords
Diabetes and Thrombosis: A Central Role for Vascular Oxidative Stress
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10050706
Abstract: Diabetes mellitus is the fifth most common cause of death worldwide. Due to its chronic nature, diabetes is a debilitating disease for the patient and a relevant cost for the national health system. Type 2… read more here.
Keywords: diabetes thrombosis; diabetes mellitus; thrombosis central; damage ... See more keywords
Oxidised Low-Density Lipoprotein-Induced Platelet Hyperactivity—Receptors and Signalling Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169199
Abstract: Dyslipidaemia leads to proatherogenic oxidative lipid stress that promotes vascular inflammation and thrombosis, the pathologies that underpin myocardial infarction, stroke, and deep vein thrombosis. These prothrombotic states are driven, at least in part, by platelet… read more here.
Keywords: modified ldl; low density; platelet hyperactivity; platelet ... See more keywords