The role of platelet hyperreactivity in venous thromboembolism after total knee arthroplasty in elderly population without pharmacologic prophylaxis: A single‐center study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.12932
Abstract: While it is suggested that platelet hyperreactivity plays a role in the arterial thrombi, its link with venous thromboembolism (VTE) is not well defined. Aggregometry using low concentrations of agonists is proposed as a reliable… read more here.
Keywords: venous thromboembolism; platelet hyperreactivity; hyperreactivity; total knee ... See more keywords
Inflammaging and platelet hyperreactivity: A new therapeutic target?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14670
Abstract: Inflammaging is defined as a chronic low-grade and systemic inflammation that accelerates the process of biological aging and is associated with many age-related diseases including cardiovascular disease (CVD), rheumatoid arthritis (RA), myeloproliferative disease, inflammatory bowel… read more here.
Keywords: platelet hyperreactivity; platelet; pro inflammatory; age related ... See more keywords
Desialylation of Platelets by Pneumococcal Neuraminidase A Induces ADP-Dependent Platelet Hyperreactivity
Sign Up to like & getrecommendations! Published in 2018 at "Infection and Immunity"
DOI: 10.1128/iai.00213-18
Abstract: Platelets are increasingly recognized to play a role in the complications of Streptococcus pneumoniae infections. S. pneumoniae expresses neuraminidases, which may alter glycans on the platelet surface. ABSTRACT Platelets are increasingly recognized to play a… read more here.
Keywords: platelet hyperreactivity; pneumococcal neuraminidase; platelet; desialylation ... See more keywords
Critical role of peroxisome proliferator-activated receptor α in promoting platelet hyperreactivity and thrombosis under hyperlipidemia.
Sign Up to like & getrecommendations! Published in 2021 at "Haematologica"
DOI: 10.3324/haematol.2021.279770
Abstract: Platelet hyperreactivity and increased atherothrombotic risk are specifically associated with dyslipidemia. Peroxisome proliferator-activated receptor alpha (PPARα) is an important regulator of lipid metabolism. It was suggested to affect both thrombosis and hemostasis, yet the underlying… read more here.
Keywords: ppar; peroxisome proliferator; hyperlipidemia; thrombosis ... See more keywords