Investigation of redox modifications of platelet integrin GPIIb-IIIa in diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.102
Abstract: Diabetes is a global health problem, affecting 382 million people worldwide. Critically, up to 70% of deaths from diabetes are due to the development of occlusive blood clots (thrombosis), leading to heart attack and stroke.… read more here.
Keywords: iiia diabetes; gpiib; integrin gpiib; gpiib iiia ... See more keywords
Coenzyme Q10 Attenuates Platelet Integrin αIIbβ3 Outside-in Signaling through Targeting cAMP/PKA Pathway and Inhibits Atherosclerosis
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DOI: 10.1182/blood-2018-99-120196
Abstract: Introduction: Platelet integrin αIIbβ3 outside-in signaling is crucial for platelet adhesion and aggregation, and contributes to atherogenesis. Coenzyme Q10 (CoQ10) has been implicated as a protective factor against cardiovascular diseases (CVDs), particularly atherosclerosis. However, whether… read more here.
Keywords: iib outside; integrin iib; coq10; platelet ... See more keywords