Injury Site Specific Xenon Delivered by Platelet Membrane-mimicking Hybrid Microbubbles to Protect Against Acute Kidney Injury via Inhibition of Cellular Senescence.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203359
Abstract: Inhalation of xenon gas improved acute kidney injury (AKI). However, xenon can only be delivered through inhalation, which causes non-specific distribution and low bioavailability of xenon, thus limiting its clinical application. In this study, xenon… read more here.
Keywords: membrane mimicking; mimicking hybrid; injury; platelet membrane ... See more keywords
Platelet Membrane-fused Circulating Extracellular Vesicles Protect the Heart from Ischemia/reperfusion Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300052
Abstract: Myocardial ischemia/reperfusion injury (I/RI) may potentiate cardiac remodeling and heart failure, while effective therapies for I/RI remain lacking. Circulating extracellular vesicles (EV) have great potential to protect against I/RI. However, effective delivery of EV in… read more here.
Keywords: reperfusion; delivery; heart; membrane ... See more keywords
Platelet membrane camouflaged nanoparticles: biomimetic architecture for targeted therapy.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120395
Abstract: Cell membrane coating strategy is one of the promising techniques for biomimetic functionalization of nanoparticle. The biomimetic nanoparticles camouflage themselves utilizing the fundamental properties of native cells. Cell membranes are extracted from various cells to… read more here.
Keywords: platelet membrane; camouflaged nanoparticles; targeted therapy; membrane camouflaged ... See more keywords
Platelet-membrane-camouflaged bismuth sulfide nanorods for synergistic radio-photothermal therapy against cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm00599d
Abstract: Bismuth-containing nanoparticles (BNPs) are potential enhancers for tumor radiotherapy. Improving the bioavailability and developing synergistic therapeutic regimens benefit the drug transformation of BNPs. In the present study, we prepare a mesoporous silica-coated bismuth nanorod (BMSNR)… read more here.
Keywords: platelet membrane; bmsnr; radiotherapy; cancer ... See more keywords
Platelet membrane-camouflaged nanovesicles targeted delivery of MLN4924 for antitumor therapy
Sign Up to like & getrecommendations! Published in 2025 at "New Journal of Chemistry"
DOI: 10.1039/d4nj04723k
Abstract: Inhibition of protein neddylation pathway has emerged an attractive anticancer strategy in pre-clinical studies. MLN4924, as a small molecule inhibitor of the neddylation, has been found to effectively inhibit the... read more here.
Keywords: membrane camouflaged; nanovesicles targeted; targeted delivery; delivery mln4924 ... See more keywords
Platelet Membrane-Coated Poly (Lactic-Co-Glycolic Acid) Nanoparticles as a Targeting Drug Delivery System for Multidrug-Resistant Breast Cancer
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s517753
Abstract: Introduction Paclitaxel (PTX), widely used chemotherapeutic agent, is limited by poor solubility, P-glycoprotein (P-gp) mediated efflux, and non-specific toxicity. To overcome these challenges, we developed a triple-functionalized nanocarrier system incorporating poly(lactide-co-glycolide) (PLGA)-based nanoparticles (PNs), D-α-tocopheryl… read more here.
Keywords: ptx; delivery; multidrug resistant; drug ... See more keywords
Platelet Membrane Biomimetic Nanoparticles Combined With UTMD to Improve the Stability of Atherosclerotic Plaques
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.868063
Abstract: Although research on the treatment of atherosclerosis has progressed recently, challenges remain in developing more effective, safer and transformative strategies for the treatment of atherosclerosis. Nanomaterials have recently played a unique role in many fields,… read more here.
Keywords: treatment atherosclerosis; stability; atherosclerotic plaques; treatment ... See more keywords
Platelet Membrane Receptor Proteolysis: Implications for Platelet Function
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2020.608391
Abstract: The activities of adhesion and signaling receptors in platelets are controlled by several mechanisms. An important way of regulation is provided by proteolytic cleavage of several of these receptors, leading to either a gain or… read more here.
Keywords: platelet membrane; platelet function; receptor; platelet ... See more keywords
Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020380
Abstract: Pain is one of the most frequent health problems, and its evaluation and therapeutic approach largely depend on patient self-report. When it is not possible to obtain a self-report, the therapeutic decision becomes more difficult… read more here.
Keywords: membrane proteins; proteins pain; pain; pain biomarkers ... See more keywords
Platelet-Membrane-Encapsulated Carvedilol with Improved Targeting Ability for Relieving Myocardial Ischemia–Reperfusion Injury
Sign Up to like & getrecommendations! Published in 2022 at "Membranes"
DOI: 10.3390/membranes12060605
Abstract: In recent years, cell membrane drug delivery systems have received increasing attention. However, drug-loaded membrane delivery systems targeting therapy in myocardial ischemia–reperfusion injury (MIRI) have been relatively rarely studied. The purpose of this study was… read more here.
Keywords: delivery; reperfusion injury; drug; platelet membrane ... See more keywords
Influence of Long-Term Soccer Training on the Fatty Acid Profile of the Platelet Membrane and Intra-Platelet Antioxidant Vitamins
Sign Up to like & getrecommendations! Published in 2024 at "Nutrients"
DOI: 10.3390/nu16152391
Abstract: This research aimed to study the long-term effects of soccer training on platelet membrane fatty acid levels and antioxidant vitamins. Forty-four subjects divided into soccer players (SP; n = 22; 20.86 ± 0.36 years) and… read more here.
Keywords: long term; soccer training; platelet; platelet membrane ... See more keywords