Platelet-to-Neutrophil ratio as a predictor of risk of complications in sickle cell disease: a valuable insight for resource-limited settings
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Hematology"
DOI: 10.1007/s00277-025-06419-6
Abstract: Sickle cell disease (SCD) presents significant clinical challenges, particularly in resource-limited settings where early identification of high-risk patients remains difficult, necessitating the use of simple, cost-effective biomarkers to improve risk stratification and guide timely interventions.… read more here.
Keywords: predictor; resource limited; neutrophil ratio; risk ... See more keywords
COVID‐19 infection‐associated platelet and neutrophil activation is blunted by previous anti‐SARS‐CoV‐2 vaccination
Sign Up to like & getrecommendations! Published in 2023 at "British Journal of Haematology"
DOI: 10.1111/bjh.18726
Abstract: The effectiveness of vaccination against SARS‐CoV‐2 in preventing COVID‐19 or in reducing severe illness in subjects hospitalized for COVID‐19 despite vaccination has been unequivocally shown. However, no studies so far have assessed if subjects who… read more here.
Keywords: vaccination; associated platelet; platelet neutrophil; platelet ... See more keywords
The Role of Platelet–Neutrophil Interactions in Driving Autoimmune Diseases
Sign Up to like & getrecommendations! Published in 2025 at "Immunology"
DOI: 10.1111/imm.13901
Abstract: Platelets and neutrophils are among the most abundant cell types in peripheral blood. Beyond their traditional roles in thrombosis and haemostasis, they also play an active role in modulating immune responses. Current knowledge on the… read more here.
Keywords: role; neutrophil interactions; platelet; platelet neutrophil ... See more keywords
Thrombin contributes to protective immunity in pneumonia‐derived sepsis via fibrin polymerization and platelet–neutrophil interactions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13625
Abstract: Essentials Immunity and coagulation are linked during sepsis but the role of thrombin is not fully elucidated. We investigated the effect of thrombin inhibition on murine Klebsiella pneumosepsis outcome. Thrombin is crucial for survival and… read more here.
Keywords: immunity; via fibrin; pneumonia derived; derived sepsis ... See more keywords
Increased Circulating Extracellular Superoxide Dismutase Attenuates Platelet-Neutrophil Interactions.
Sign Up to like & getrecommendations! Published in 2024 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2024-0292oc
Abstract: Acute respiratory distress syndrome (ARDS) is a serious illness accounting for 10% of ICU admissions and high mortality of 31-45% with a paucity of pharmacologic treatment options. Dysregulated inflammation and oxidative stress are hallmark features… read more here.
Keywords: increased circulating; platelet activation; platelet neutrophil; superoxide dismutase ... See more keywords
Increased platelet–neutrophil aggregate ratio after severe acute respiratory syndrome coronavirus 2 vaccination and severe infection
Sign Up to like & getrecommendations! Published in 2025 at "Science Progress"
DOI: 10.1177/00368504251352079
Abstract: Objectives Platelet–neutrophil aggregates (PNA) bridge inflammatory processes with the hemostatic system. The goal of this study was the comparative evaluation of PNAs in healthy individuals vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), septic… read more here.
Keywords: acute respiratory; syndrome coronavirus; platelet neutrophil; respiratory syndrome ... See more keywords