Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-022-07325-z
Abstract: Obese patients exhibit an overall increased platelet reactivity and a reduced sensitivity to antiplatelet therapy. The aim of this study is to evaluate the platelet reactivity measured by impedance aggregometry in overweight and obese patients… read more here.
Keywords: overweight obese; therapy; platelet; platelet reactivity ... See more keywords
β-Amyloid and mitochondrial-derived peptide-c are additive predictors of adverse outcome to high-on-treatment platelet reactivity in type 2 diabetics with revascularized coronary artery disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02060-4
Abstract: Background and aims Increased β-amyloid and decreased mitochondrial-derived peptide (MOTS-c), are reported in diabetes. We investigated their additive value to high on-clopidogrel platelet reactivity (HPR) for adverse outcome in type 2 diabetics after recent revascularization.… read more here.
Keywords: adverse outcome; type diabetics; platelet; platelet reactivity ... See more keywords
High on-treatment platelet reactivity and outcome in elderly with non ST-segment elevation acute coronary syndrome - Insight from the GEPRESS study.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.01.057
Abstract: BACKGROUND Elderly treated with dual antiplatelet therapy after percutaneous coronary intervention (PCI) represent a challenging population because of increased risk of both ischemic and bleeding events. We aimed to investigate the association between high on-treatment… read more here.
Keywords: mace; year; hpr; platelet reactivity ... See more keywords
Ticagrelor versus clopidogrel in patients undergoing implantation of paclitaxel-eluting stent in the femoropopliteal district: A randomized pilot study using frequency-domain optical coherence tomography.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2020.01.024
Abstract: OBJECTIVES Aim of this study was to evaluate different response in platelet reactivity and vessel healing using high-resolution frequency-domain optical coherence tomography (FD-OCT) in patients with femoropopliteal artery disease treated with ZILVER PTX drug eluting… read more here.
Keywords: domain optical; optical coherence; ticagrelor; group ... See more keywords
Serum Brain-Derived Neurotrophic Factor is Related to Platelet Reactivity and Metformin Treatment in Adult Patients With Type 2 Diabetes Mellitus.
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DOI: 10.1016/j.jcjd.2018.01.014
Abstract: OBJECTIVES The aim of this study was to investigate the association of serum brain-derived neurotrophic factor (BDNF) levels with platelet reactivity and antidiabetes treatment, as well as serum adipocytokine concentrations. METHODS This observational, open-label study… read more here.
Keywords: reactivity; treatment; bdnf levels; platelet reactivity ... See more keywords
Residual platelet reactivity in low-dose aspirin-treated patients with class 1 obesity.
Sign Up to like & getrecommendations! Published in 2020 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2020.106819
Abstract: BACKGROUND Recent data suggest a decreased clinical efficacy of low-dose aspirin in patients weighing ≥70 kg. We therefore investigated the impact of body weight and class 1 obesity on thromboxane generation and platelet reactivity to arachidonic… read more here.
Keywords: platelet; class obesity; platelet reactivity;
Impact of high on-treatment platelet reactivity after angioplasty in patients with critical limb ischemia.
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DOI: 10.1016/j.vph.2021.106925
Abstract: OBJECTIVES Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard of care in patients with peripheral artery disease (PAD) after percutaneous transluminal angioplasty (PTA). However, high on treatment platelet reactivity (HTPR) to DAPT is… read more here.
Keywords: patients critical; high treatment; limb; htpr ... See more keywords
Net platelet clot strength of thromboelastography platelet mapping assay for the identification of high on-treatment platelet reactivity in post-PCI patients
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DOI: 10.1042/bsr20201346
Abstract: Abstract High-on treatment platelet reactivity (HTPR) leads to more prevalence of thrombotic event in patients undergoing percutaneous coronary interventions (PCI). Dual antiplatelet therapy with aspirin in addition to one P2Y12 inhibitor is commonly administrated to… read more here.
Keywords: high treatment; treatment; platelet reactivity; platelet mapping ... See more keywords
Peri-Procedural Platelet Reactivity in Percutaneous Coronary Intervention.
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DOI: 10.1055/s-0038-1649484
Abstract: Platelet activation and aggregation play a pivotal role in thrombotic complications occurring during percutaneous coronary intervention (PCI), and peri-PCI anti-platelet therapy represents a standard of care. High platelet reactivity prior to PCI has been correlated… read more here.
Keywords: anti platelet; platelet reactivity; percutaneous coronary; pci ... See more keywords
On-treatment platelet reactivity in peripheral and coronary blood in patients undergoing primary PCI for ST-segment elevation myocardial infarction (STEMI)
Sign Up to like & getrecommendations! Published in 2018 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2018.1455220
Abstract: Abstract Dual antiplatelet therapy is recommended in patients undergoing primary percutaneous coronary intervention (p-PCI) for ST-segment elevation myocardial infarction (STEMI). Pre-analytical variables may influence platelet function analysis results. Our aim was to evaluate the on-treatment… read more here.
Keywords: patients undergoing; platelet reactivity; blood; test ... See more keywords
Relation Between Platelet Reactivity Levels and Diabetic Retinopathy Stage in Patient with Type 2 Diabetes Mellitus by Using Multiplate Whole Blood Aggregometry
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DOI: 10.1080/08820538.2021.1893759
Abstract: ABSTRACT Purpose: To test the hypothesis of a possible association between platelet reactivity and the severity of diabetic retinopathy using Multiplate whole blood aggregometry in type 2 diabetes mellitus patients. Methods: Of 157 patients were… read more here.
Keywords: diabetic retinopathy; group; platelet reactivity; blood ... See more keywords