Basic mechanisms of platelet receptor shedding
Sign Up to like & getrecommendations! Published in 2017 at "Platelets"
DOI: 10.1080/09537104.2016.1235690
Abstract: Abstract Proteolytic shedding of the extracellular ectodomain of platelet receptors provides a key mechanism for irreversible loss of ligand-binding capacity, and for regulating platelet function in health and disease. Platelets derived from megakaryocytes are small… read more here.
Keywords: basic mechanisms; platelet receptor; receptor shedding; mechanisms platelet ... See more keywords
Menstrual and obstetrical bleeding in women with inherited platelet receptor defects—A systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Haemophilia"
DOI: 10.1111/hae.13927
Abstract: Women with inherited platelet receptor defects (IPRD) may have an increased risk of heavy menstrual bleeding (HMB) and postpartum haemorrhage (PPH). read more here.
Keywords: receptor defects; inherited platelet; women inherited; platelet receptor ... See more keywords
Tetherin/BST2, a physiologically and therapeutically relevant regulator of platelet receptor signalling.
Sign Up to like & getrecommendations! Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2020003182
Abstract: The reactivity of platelets, which play a key role in the pathogenesis of atherothrombosis, is tightly regulated. The integral membrane protein tetherin/bone marrow stromal antigen-2 (BST-2) regulates membrane organization, altering both lipid and protein distribution… read more here.
Keywords: receptor; tetherin bst; bst; platelet receptor ... See more keywords