Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes
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DOI: 10.1126/sciadv.aaz1580
Abstract: Platelet-monocyte “adhesion synapse” initiates physiologic biogenesis of cross-presenting dendritic cells. Dendritic cells (DCs) are adept at cross-presentation and initiation of antigen-specific immunity. Clinically, however, DCs produced by in vitro differentiation of monocytes in the presence… read more here.
Keywords: platelet selectin; presentation; cross presentation; differentiation ... See more keywords