Articles with "platform genetic" as a keyword



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An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes.

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Published in 2017 at "Nature chemical biology"

DOI: 10.1038/nchembio.2312

Abstract: In this study, we demonstrate the feasibility of expanding the genetic code of Escherichia coli using its own tryptophanyl-tRNA synthetase and tRNA (TrpRS-tRNATrp) pair. This was made possible by first functionally replacing this endogenous pair… read more here.

Keywords: trprs trnatrp; code expansion; platform genetic; code ... See more keywords